Bioengineering Distinguished Seminar: Vincent Rotello

Friday, March 11, 2016
9:00 a.m.-10:00 a.m.
Room 2108, Chemical and Nuclear Engineering Building
Dr. Christopher Jewell
cmjewell@umd.edu

Dr. Vincent Rotello
Charles A. Goessmann Professor of Chemistry and University Distinguished Professor 
Department of Chemistry
University of Massachusetts - Amherst

Interfacing Nanomaterials with Biology: Applications in Therapeutics and Diagnostics 

A key issue in the use of nanomaterials is controlling how they interact with themselves and with the outer world. Our research program focuses on the tailoring of nanoparticles of surfaces for a variety of applications, coupling the atomic-level control provided by organic synthesis with the fundamental principles of supramolecular chemistry. Using these nanoparticles, we are developing new strategies for biological applications This talk will focus on the interfacing of nanoparticles with biosystems, and will discuss the application of self-asssembled nanoparticles as delivery vehicles, demonstrating the use of nanoparticle-based capsules for direct delivery of small molecules, proteins, and nucleic acids into the cytosol.  Finally, this presentation will also feature the use of nanoparticles for diagnostic applications, focusing on using selective nanoparticle-protein interactions to generate array-based ("chemical nose") sensors for detection of cancer and high throughput screening of therapeutic agents.


About the Speaker

Vincent Rotello is the Charles A. Goessmann Professor of Chemistry and a University Distinguished Professor at the University of Massachusetts at Amherst. He received his B.S. in Chemistry in 1985 from Illinois Institute of Technology, and his Ph. D. in 1990 in Chemistry from Yale University. He was an NSF postdoctoral fellow at Massachusetts Institute of Technology from 1990-1993, and joined the faculty at the University of Massachusetts in 1993. He has been the recipient of the NSF CAREER and Cottrell Scholar awards, as well as the Camille Dreyfus Teacher-Scholar, the Sloan Fellowships, and the Langmuir Lectureship, and is a Fellow of the American Association for the Advancement of Science (AAAS) and of the Royal Society of Chemistry (U.K.). He is also recognized in 2014 and 2015 by Thomson Reuters as one of the “Most Influential Scientific Minds”. He is currently the Editor in Chief of Bioconjugate Chemistry, and is on the Editorial Board of 14 other journals. His research program focuses on using synthetic organic chemistry to engineer the interface between hard and soft materials, and spans the areas of devices, polymers, and nanotechnology/bionanotechnology, with over 460 peer-reviewed papers published to date. He is actively involved in the development of new nanomanufacturing methods, and in the area of bionanotechnology his research includes programs in delivery, imaging, diagnostics and nanotoxicology.

 

 

  

Audience: Public 

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