Associate Professor Keith Herold, Bioengineering, University of Maryland

Associate Professor Keith Herold

Herold Ph.D., Ohio State University, 1985

Room 1145 Engineering Lab Building
E-mail: herold@umd.edu
Phone: (301) 405-5268
Fax: (301) 314-9477

Associate Professor Keith Herold joined the University of Maryland's Department of Mechanical Engineering in 1987, where his research focused on energy systems and absorption refrigeration. In 2000, he shifted his focus to bioengineering and began exploring biosensors, microarrays, and related lab-on-a-chip technologies. In 2006 he joined the newly formed Fischell Department of Bioengineering, where his work in these areas continues. His current research projects include collaborations with the FDA on a DNA-based pathogen biosensor, and with electrophysiologists at the University of Maryland School of Medicine on the analysis of patients suffering from ventricular tachycardia.

Research Interests

BioMEMS, microfluidic systems for bioanalytical assays, heat and mass transfer in bioengineering.

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Recent Publications

Rasooly, A., Herold, K.E., 2008, "Food microbial pathogen detection and analysis using DNA microarray technologies", Foodborne Pathogens and Disease, 2nd revision submitted May 08.

Rasooly, A., Sergeev, N., Herold, K.E., 2007, "Biosensor technologies for microbial and environmental analysis", Minerva Biotecnologica, Vo. 19, No. 3, pp. 105-116.

Kyung, I.-S., Herold, K.E., Kang, Y. T., 2007 , "Experimental verification of H₂O/LiBr absorber bundle performance with smooth horizontal tubes", Int. J. Refrigeration, Vol. 30, pp. 582-590.

Kyung, I.-S., Herold, K.E., Kang, Y. T., 2007, "Model for absorption of water vapor into aqueous LiBr flowing over a horizontal smooth tube", Int. J. Refrigeration, Vol. 30, pp. 591-600.

Rasooly, A., Herold, K.E., 2006, "Biosensors for the Analysis of Food and Water Borne Pathogens and their Toxins", J. of AOAC International, Vol. 89, No. 3, pp. 873-883.

Yuan, Z., Herold, K.E., 2005, "Specific Heat Measurements on Aqueous Lithium Bromide", International J. Heating, Ventilating, Air-Conditioning and Refrigeration, Vol. 11, No. 3, pp. 361-375.

Yuan, Z., Herold, K.E., 2005, "Thermodynamic Properties of Aqueous Lithium Bromide Using a Multiproperty Free Energy Correlation", International J. Heating, Ventilating, Air-Conditioning and Refrigeration, Vol. 11, No. 3, pp. 377-393.

Herold, K.E., Rasooly, A., 2003, "Oligo Design, A Computer Program for Development of Probes for Oligonucleotide Microarrays", BioTechniques, Vol. 35, No. 6, pp. 1216-1218,1220-1221.

Buran, B., Butler, L., Currano, A., Smith, E., Tung, W., Cleveland, K., Buxton, C., Lam, D., Obler, T., Rais-Bahrami, S., Stryker, M., Herold, K.E., 2003, "Environmental Benefits of Implementing Alternative Energy Technologies in Developing Countries", Applied Energy, Vol. 76, Issues 1-3, pp. 89-100.

Zhou, X., Yuan, Z., Herold, K.E., 2001, "Phase Distribution of the Surfactant 2-Ethyl-Hexanol in Aqueous Lithium Bromide", International J. Heating, Ventilating, Air-Conditioning and Refrigeration, Vol. 8, No. 4, pp. 371-381.

Ghosh, K., Zhou, X., Herold, K.E., 2002, "Circulation of 2-Ethyl-Hexanol in an Absorption Chiller", ASHRAE Transactions, Vol. 108, Pt. 1, pp. 861-866.

Kyung, I.-S., Herold, K.E., "Performance of a Horizontal Smooth Tube Absorber with and without 2-Ethyl-Hexanol", Journal of Heat Transfer, Vol. 124, pp. 177-183, February 2002.

Yuan, Z., Herold, K.E., "Surface Tension of Aqueous Lithium Bromide with Controlled Vapor Concentration of 2-ethyl-hexanol", ASHRAE Transactions, Vol. 107, Part 1, pp. 463-468, 2001.

Yuan, Z., Herold, K.E., "Surface Tension of Pure Water and Aqueous Lithium Bromide with 2-ethyl-hexanol", Applied Thermal Engineering, Vol. 21, No. 8, pp. 881-897, June 2001.

Kulankara, S. Herold, K.E., "Surface Tension of Aqueous Lithium Bromide with Heat/Mass Transfer Additives", Int. J. Refrigeration, Vol. 25, Issue 3,pp. 383-389, 2002.

Kulankara, S., Herold, K.E., "Theory of Heat/Mass Transfer Additives in Absorption Chillers", ASHRAE Transactions, Vol. 107, Pt. 1, pp. 305-315, 2001.

Kulankara, S., Herold, K.E., "Theory of Heat/Mass Transfer Additives in Absorption Chillers", International J. Heating, Ventilating, Air-Conditioning and Refrigeration Research, Vol. 6, No. 4, pp. 369-380, October 2000.

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Books

Natural Gas-Fired Cooling Technologies and Economics, K.E. Herold, E. de los Reyes, L. Harriman, D.V. Punwani, W.A. Ryan, Gas Technology Institute, 2005, 286 pages, www.gastechnology.org/gascooling/gti.html.

Absorption Chillers and Heat Pumps, K.E. Herold, R. Radermacher and S.A. Klein, CRC Press, 1996, 350 pages, original edition.

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Book Chapters

Rasooly, A., Herold, K.E., 2008, "Application of DNA Microarray Technology for Microbial Analysis", chapter 6 in Nano and Microsensors for Chemical and Biological Terrorism Surveillance, edited by J. B.-H. Tok, Royal Society of Chemistry, galley proof stage, pp. 111-151.

Herold, K.E., Rasooly, A., 2008, "Oligonucleotides as Recognition and Catalytic Elements", chapter in book edited by Mahmmad Zourob, submitted.

Herold, K.E., and Rasooly, A., 2008, "PCR paper ****", chapter in Biosensors, a volume in the series Methods in Molecular Biology, Humana Press, submitted.

Kostov, Y., Sergeev, N., Wilson, S., Herold, K.E., and Rasooly, A., 2008, "A simple portable electroluminescence illumination based CCD detector", chapter in Biosensors, a volume in the series Methods in Molecular Biology, Humana Press, submitted.

Sergeev, N., Herold, K.E., Rasooly., A, 2007, "Regulatory and validation issues for biosensors and related bioanalytical technologies", Chapter 86 in Handbook of Biosensors and Biochips, John Wiley & Sons Ltd Publishers, Vo2. 2, pp. 1289-1303.

Herold,K.E., 2007, "Absorption Heat Pumps for Waste Heat Recovery Applications ", chapter in Encyclopedia of Energy Engineering and Technology, edited by Barney Capehart, Taylor and Francis, Vol. 3, pp. 1541-1547.

Al-Khaldi, S.F., Mossoba, M.M., Myers, K., Herold, K.E., Hart, S.J., and Terray, A., 2006, "Using Micro- and Nano- Technology in Bacterial Isolation and Identification from Complex Food Matrices", Chapter 6 in New Developments in Nutrition Research, NOVA Science Publishers, pp. 135-167.

Sergeev, N., Herold, K.E., Rasooly, A., 2006, "Microarray Analysis of Microbial Pathogens", Chapter 17 in Encyclopedia of Rapid Microbiological Methods, Vol. 3, pp. 363-405.

Rasooly, A., Herold, K.E., 2006, "Biosensors for Microbial Diagnostics", Chapter 18 in Encyclopedia of Rapid Microbiological Methods, Vol. 3, pp. 407-448.

Sergeev, N., Rasooly, A., Herold, K.E., 2005, "Oligonucleotide Design For PCR Primers And Microarray Probes", chapter in Encyclopedia of Medical Genomics and Proteomics, Vol. 2, pp. 938-942.

Herold, K.E., "Heat Transfer", Chapter 12 in An Engineer’s Guide to Matlab, Prentice Hall, 2000, pp. 517-570, second edition 2005, pp. 554-602.

Honors and Awards

Fellow, American Society of Mechanical Engineers