BIOE Seminar Series: Claus-Michael Lehr (Saarland University, Germany)

Friday, September 25, 2020
9:00 a.m.-10:00 a.m.
Virtual
Katharina Maisel
maiselka@umd.edu

Join us for the Bioengineering Seminar Series, which connects experts from around the country with our faculty, students, and staff to discuss their recent findings. Everyone is welcome!

The Fall 2020 seminars will be held virtually on Fridays from 9:00 a.m. – 9:50 a.m., unless otherwise noted. All BIOE faculty, students, staff, postdocs, and affiliates as well as additional subscribers to our weekly seminars emails will receive Zoom event information the week of each seminar. 

If you do not yet receive our weekly seminars email and would like to subscribe to the listserv, or if there is a particular seminar listed below that you would like to attend, please email Emily Rosenthal

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Dr. Claus-Michael Lehr
Saarland University (Germany)

Drug Delivery across biological barriers for combatting and preventing infectious diseases

Infectious diseases are on the rise and pose increasing challenges to human health with mortality rates predicted to soon exceed those of cancer and other diseases. While antimicrobial resistance is increasing, the number of new antibiotics and even the number of companies engaging in those is decreasing. Besides the need for new targets and molecules for anti-infective compounds, such as e.g. pathoblockers, there is also a need to deliver those across biological barriers preventing access to the target site. Relevant barriers in this context are the body’s outer epithelia, in particular of the gut, the skin and the lung, but also host cell membranes, the bacterial cell envelope as well as non-cellular barriers, such as mucus and bacterial biofilms. The lecture will provide an introduction into this exciting field of research with focus on novel nanomedicines as innovative human cell- and tissue models as alternative to animal testing

About the Speaker
Claus-Michael Lehr is a Professor at Saarland University as well as co-founder and head of the department Drug Delivery at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS).  Lehr has also been the co-founder of Across Barriers GmbH and acts as CEO of PharmBioTec GmbH, a not-for-profit contract research subsidiary of Saarland University. The research theme of his team is non-invasive drug delivery across biological barriers, in particular, the epithelia of the gastrointestinal tract, the skin, and the lungs. More recently, this approach has been expanded to microbial barriers. He is (co)author of more than 400 papers with >18.000 citations (h‐index = 74). He is co‐editor of Europ. J. of Pharmaceutics and Biopharmaceutics and initiated the biannual conference "Biological Barriers." The British magazine The Medicine Maker rated him three times as one of the top 100 most influencing drug researchers in the world.

Audience: Public 

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