The newly established BioWorkshop is hosted by the Fischell Department of Bioengineering in the A. James Clark Hall. The core facility offers access to an array of cutting-edge scientific instruments spanning from Biological Imaging, Cellular and Biochemical Analysis to Biomaterial Characterization, and Histology. Bioimaging instruments include a FLIM&FCS-capable laser scanning confocal microscope (LSCM), a fully-automated wide-field fluorescence microscope, an atomic force microscope for biological sample (BioAFM), a benchtop scanning&transmission electron microscope (SEM&TEM) and a microCT for fixed and live imaging. Cellular and Biochemical Analysis tools provide an imaging flow cytometer, a flow cytometer analyzer, a Gel Permeation Chromatography (GPC), one UHPLC, one qPCR, one lyophilizer, a multi-mode plate reader with incubation system, and Biacore surface plasmon resonance scanner (SPR). Biomaterial Characterization tools include FT-IR, rheometer, dynamic mechanical analyzer, particle sizer and zeta-potential analyzer (DLS), and circular dichroism spectrometer. Additionally, a complete histology suite including cryostat is also available. Trained users have access to the instruments 24/7.
Contact BioWorkshop director Dr. Christopher Jewell for more information.
The fabrication of complex engineered tissues remains a grand challenge in regenerative medicine. These complex tissues – bone, cartilage, vasculature, and cardiac – are characterized by dense cellularity, patterned cellular composition, and controlled matrix presentation. Mimicking this native complexity within in vitro cell-based constructs and biomaterial formulations has enormous potential for clinical applications towards repair and regeneration of tissues. CECT addresses this clinical opportunity by applying 3D printing strategies to produce novel tissue engineered constructs with transplantation capabilities. The center brings together research leaders at the University of Maryland, Rice University, and Wake Forest Institute for Regenerative Medicine, known for their strong bioengineering and biofabrication expertise, state-of-the-art resources, and translational experience.
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The Center of Excellence in Regulatory Science and Innovation (M-CERSI), funded by the U.S. Food and Drug Administration, focuses on modernizing and improving the ways drugs and medical devices are reviewed and evaluated. This center is a collaborative partnership between the University of Maryland, College Park, and the University of Maryland, Baltimore. Researchers from both campuses work with FDA staff to support the development of new tools, standards and approaches to assess the safety, efficacy, quality and performance of FDA-regulated products.
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The Robert E. Fischell Institute for Biomedical Devices seeks to catalyze the transformation of basic research into clinical practice and commercial success. The Institute drives innovation by immersing creative and energetic scientists and engineers in a nurturing and rewarding research environment where engineered health systems are conceived of and investigated. The Institute is comprised of staff, resources, facilities, and a “network of experts” who facilitate not only prototyping and manufacturing expertise, but who also facilitate venture creation, intellectual property creation, and product passage through various clinical, regulatory and reimbursement hurdles.
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