BIOE Seminar Series: Gordana Vunjak-Novakovic (Columbia University)

Friday, April 2, 2021
9:00 a.m.-10:00 a.m.
Virtual
Shawn He
shawnhe@umd.edu

The Spring 2021 seminars will be held virtually on Fridays from 9:00 a.m. – 9:50 a.m., unless otherwise noted. All BIOE faculty, students, staff, postdocs, and affiliates as well as additional subscribers to our weekly seminars emails will receive Zoom event information the week of each seminar. 

If you do not yet receive our weekly seminars email and would like to subscribe to the listserv, or if you would like to attend this particular seminar, please email Emily Rosenthal

________________________________________________________________________

Engineering Human Tissues for Medical Impact

 
The Mikati Foundation Professor of Biomedical Engineering and Medicine
Columbia University
 
About the Speaker

Gordana Vunjak-Novakovic is University Professor, the highest academic rank at Columbia University and the first engineer at Columbia to receive this distinction. The focus of her lab is on engineering functional human tissues for use in regenerative medicine and in patient-specific “organs-on-a-chip” for studies of human pathophysiology. She is well published and highly cited (h=128), mentored over 150 trainees, and launched four start-up companies with her students. She is a member of Academia Europaea, Serbian Academy of Arts and Sciences, National Academy of Engineering, National Academy of Medicine, National Academy of Inventors, and the American Academy of Arts and Sciences.

Abstract 

Tissue engineering involves an integrated use of human stem cells, biomaterial scaffolds (providing a structural and logistic template for tissue formation) and bioreactors (providing environmental control, dynamic sequences of molecular and physical signaling). In general, our engineering designs are based on biological principles, in order to enable and direct the cells to perform specific functions, in the context of tissue development, regeneration and disease. In regenerative medicine, this approach allows us to tailor the tissue grafts to the patient and the condition being treated. Another tissue engineering paradigm is emerging in recent years, with the development of “organs on a chip” platforms for modeling integrated human physiology. These platforms use micro-sized human tissues that can be functionally connected by vascular perfusion. Derivation of all component cells (tissue specific, supporting, vascular and immune) from iPS cells allows individualized approaches to modeling disease. To illustrate the state of the art in the field and reflect on some of the current challenges and opportunities, this talk will discuss some recent advances in bioengineering of anatomically correct bone, whole lung and patient-specific “organs on a chip” for studies of human patho/physiology.

 


remind we with google calendar

 

March 2024

SU MO TU WE TH FR SA
25 26 27 28 29 1 2
3 4 5 6 7 8 9
10 11 12 13 14 15 16
17 18 19 20 21 22 23
24 25 26 27 28 29 30
31 1 2 3 4 5 6
Submit an Event