Event
Special Bioengineering Seminar: Ji-Xin Cheng
Thursday, January 24, 2013
11:00 a.m.
Room 1105 Jeong H. Kim Engineering Building
Professor Ian White
ianwhite@umd.edu
Offering New Solutions to Medicine via Spectroscopic Imaging
Ji-Xin Cheng
Weldon School of Biomedical Engineering
Purdue University
Current clinical diagnosis tools including computed tomography, magnetic resonance imaging, and ultrasonic tomography provides little chemical information, whereas human diseases are driven by alterations of molecular mechanisms. This gap makes it difficult to judge aggressiveness of a prostate tumor or vulnerability of an atherosclerotic plaque. Spectroscopic imaging, in which inherent molecular fingerprint signals are used as contrast, is opening a new window for seeing the unseen inside single cells and in vivo tissues. I will present our most recent advances in development and applications of label-free spectroscopic imaging techniques, including detection of cardiovascular plaques by bond-selective photoacoustic imaging and finding of altered cholesterol metabolism in aggressive cancer by coherent Raman scattering microscopy. Potentially transformative impacts of these projects will be illustrated.
