Event
Bioengineering Seminar Series: Peter Tessier
Friday, November 20, 2015
9:00 a.m.-10:00 a.m.
Pepco Room (1105), Jeong H. Kim Engineering Building
Dr. Steven Jay
smjay@umd.edu
Peter Tessier
Richard Baruch M.D. Career Development Associate Professor
Chemical and Biological Engineering
Rensselaer Polytechnic Institute
Improved methods for designing, evolving and selecting antibodies
The biotech industry has seen an explosion in the development of therapeutic antibodies in the last decade. The advantages of antibodies – namely their potency, specificity, low toxicity, stability, ease of generation of lead candidates and use of similar manufacturing processes to generate diverse variants – are compelling. Nevertheless, there are many challenges associated with antibody development that require key technical advances to simplify the rapid and reliable generation of potent antibody therapeutics. I will discuss our progress in addressing some of these challenges, including the design, evolution and selection of antibodies with high affinity, stability and solubility.
