BIOE Seminar Series: Xiaoming (Shawn) He

Friday, March 2, 2018
9:00 a.m.-10:00 a.m.
A. James Clark Hall, Room 2132
Dr. Steven Jay
smjay@umd.edu

Dr. Xiaoming (Shawn) He
Professor, Fischell Department of Bioengineering
University of Maryland

Bioinspired Multiscale Systems for Cancer Theranostics and Tissue Regeneration  

Over the past decades, tremendous advancements have been made in discovering new therapeutic agents for medicine from the traditional small molecules to peptides/proteins, genetic materials, and more recently cells and tissues. However, the challenge to safely and effectively deliver these agents from their procurement to the clinical use in human body is still enormous. The issues range from poor bioavailability, systemic toxicity, and low specificity for the acellular agents, to poor survival after long-term storage, non-physiological cultivation in vitro, and immune rejection in vivo for cell-based medicine. We have been working on addressing these issues facing today’s medicine using a bioinspired multiscale engineering approach. In this talk, I will show our recent data on developing and utilizing novel bioinspired multiscale systems to engineer various normal and cancer stem cells and immune cells for treating ischemic diseases, modulating immune reactions, and fighting against cancer.
 

Audience: Public 

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