Bioengineering Seminar Series: George T. Gillies

Wednesday, September 19, 2007
11:00 a.m.
2108 Chemical and Nuclear Engineering Building
Professor J. Helim Aranda-Espinoza
(301) 405-8250
helim@umd.edu

Magnetically Guided Navigation of Catheters within the Body: The Development of a Clinical Tool for Cardiology and Neurosurgery

Presented by George T. Gillies
Research Professor, Physics/BME/MAE, University of Virginia
Clinical Professor, Neurosurgery, Virginia Commonwealth University

In 1984, we began a research program aimed at developing a new neurosurgical technique for the treatment of the primary malignant brain tumor glioblastoma multiforme. The concept as foreseen at the time was one of magnetically manipulating a small surgical implant through the bulk brain tissues under precision image-guidance, for the purpose of delivering a localized dose of hyperthermia to a deep-seated brain tumor. As the engineering and medical aspects of the work went forward over the following 10 years, developments in the associated technology were driven by a number of forces, both clinical and financial. The result was that when the first fully-engineered magnetic surgical systems were FDA-approved in 2002, the applications for them shifted quickly to cardiological electrophysiology which is a rapidly expanding field that presented a significant commercial opportunity for technology transfer. The talk will cover the early history of the project, the translational work needed to obtain FDA approval, and the present status of the field, along with some discussion of the directions in which the new parts of the work are heading. It will close with some comments on the practical realities of the technology transfer process, as applied to academically-sourced projects that are targeted for the commercial marketplace.

Audience: Graduate  Undergraduate  Faculty  Post-Docs 

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