Event
Bioengineering Seminar Series: Antonios G. Mikos
Wednesday, September 29, 2010
4:00 p.m.
Pepco Room, Kim Engineering Building
Professor John Fisher
jpfisher@umd.edu
Advancing Biomaterial Strategies for Bone Tissue Engineering
Antonios G. Mikos
Department of Bioengineering
Rice University
Biomaterial strategies for bone tissue regeneration range from the production of novel biodegradable, cytocompatible tissue engineering scaffolds that can be tailored with appropriate mechanical and biological signals to regenerate bone tissue in specific sites in the body to applying existing biomaterials approved for use in certain clinical applications in approaches to encourage bone tissue regeneration. For example, our laboratory has developed a variety of biodegradable polymers for the controlled delivery of biologically active agents and/or progenitor stem cell populations to promote regeneration of tissues such as bone. Further, our laboratory has explored the application of bioreactor culture of progenitor cell populations to produce extracellular matrix constructs containing biologically active signals to direct cellular differentiation and tissue formation. This talk will present recent examples of biomaterials from our laboratory to illustrate designer approaches for tissue engineering scaffolds, as well as examples of emerging applications of clinically available biomaterials as components of strategies to promote bone tissue regeneration.
