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Undergraduate Program: Courses in Bioengineering


Questions about the undergraduate program in bioengineering may be sent to

undergrad handbook

Download the BioE Undergraduate Handbook (PDF)

Courses offered by the Fischell Department of Bioengineering are listed under the heading "BIOE" in the course catalog and on Testudo. Descriptions of all BIOE undergraduate courses are included below. Students may also wish to consult our list of approved Technical Electives for BIOE majors.

When selecting courses, students should follow the four-year Sample Program as closely as possible. Since the courses build on each other, students who stray from the suggested curriculum run the risk of not being able to complete the degree in four years.

Prerequisite courses must be successfully completed (C- or better) before taking courses that require them. Students may also wish to view the undergraduate program course prerequisites chart (PDF). Questions regarding prerequisite equivalents or exceptions should be addressed to the student’s advisor.

Any other questions about courses may be sent to



Course Number
Course Title/Description
BIOE  120 Biology for Engineers
Prerequisite: permission of department. Introduction to the functions and interactions of biological systems from a quantitative perspective. Introduction to the modern experimental techniques and methods of data analysis. Roles for bioengineers in biology, and the role of biology in bioengineering will be elucidated. Students will be introduced to the functions and interactions of biological systems from a quantitative perspective. They will also be encourage d to solve problems through active inquiry, critical analysis, and creativity. Finally, roles for bioengineers in biology, and the role of biology in bioengineering will be elucidated.
BIOE 121 Biology for Engineers Laboratory
This course will build on the material covered in BIOE120. Experiments conducted in this laboratory course will cover topics such as biomechanical principles, biochemical methods, genetics and selection, scaling, microcosm interactions, human factors and imaging.
BIOE 221 Introduction to the Bioengineering Major
Prerequisite: BIOE120 and BIOE121. Introduces students to the bioengineering field through views from faculty, students, and professionals. Guides students through the BIOE major and elective tracks. Helps students with their own academic planning and career preparation.
BIOE 232 Bioengineering Thermodynamics
Prerequisite: PHYS260 and PHYS261. Credit will be granted for only one of the following: BIOE232, ENME232, ENES232 or ENME320. A quantitative introduction to thermodynamic analysis of bioengineering systems. Bioengineering encompasses a wide range of applications from nanoscale interactions (e.g. reactions between molecules), to cellular interactions (e.g. membrane electrical currents), to overall balances on organisms, all the way to large scale manufacturing. Each of these applications (and many others not mentioned) involve energy interactions which is the domain of thermodynamics. The basic laws of thermodynamics will be introduced and explained through a series of examples related to bioengineering systems.
BIOE 241 Biocomputational Methods
Prerequisite: permission of department. Credit will be granted for only one of the following: BIOE241 or ENBE241. Formerly ENBE241. Application of computer technology to biological and natural resource systems considering engineering aspects. Designed to help students in the use of computer technology for problem solving. The course will cover 4-5 software packages important for later use by the student.
BIOE 331 Biofluids
Prerequisite: BIOE120, BIOE121, BIOE241, MATH246; and one of the following: ENME232, ENME320 or BIOE232; and permission of department. Also offered as ENME331. Credit will be granted for only one of the following: BIOE331 ENCE305, or ENME331. Principles of fluid mechanics. Mass, momentum and energy conservation. Hydrostatics. Control volume analysis. Internal and external flow. Boundary layers. Modern measurement techniques. Computer analysis. Laboratory experiments.
BIOE 332 Transport Process Design
Prerequisites: BIOE120, BIOE121, BIOE241, MATH246. Pre- or co-requisite: BIOE 331; and permission of department. Credit will be granted for only one of the following: ENBE454, ENBE603, or BIOE332. Formerly ENBE454. Fluid flow, heat transfer, and mass transfer with applications in medicine, environment, biotechnology, food, agriculture, and other biosystems. Design of solutions to current problems in biological engineering is emphasized.
BIOE 340 Modeling Physiological Systems and Lab
Prerequisites: BIOE120, BIOE121, BIOE241, MATH246, and BSCI330; and permission of department. Credit will be granted for only one of the following: BIOE340 or (BSCI440 and BSCI441). Topics covered will include cell and general physiology, membrane physiology, blood cells and clotting, circulation, metabolism, respiration, and the nervous system. A lab component will also be included.
BIOE 371 Linear Algebra and ODEs in Bioengineering
Pre/corequisite: MATH246; and permission of department. This class utilizes fundamentals in linear algebra, including eigenvalues and eigenvectors, as well as linear differential equations, to study various problems in bioengineering and biological systems, with a particular emphasis on feedback, stability, controllability, and control design.
BIOE 372 Biostatistics for Experimental Design and Data Analysis
Prerequisites: BIOE120, BIOE121, BIOE241; and permission of department. This course will instruct students in the fundamentals of probability and statistics through examples in biological phenomenon, the design of bioengineering experiments, and clinical data analysis. Fundamentals covered in the course include probability distributions, hypothesis testing, power analysis, regression analysis, and correlation analysis.
BIOE 399 Independent Study in Bioengineering
BIOE 404 Biomechanics
Prerequisites: BIOE120, BIOE121, BIOE241, ENES102, MATH246; and permission of department. Introduction to the fundamentals of biomechanics including force analysis, mechanics of deformable bodies, stress and strain, multiaxial deformations, stress analysis, and viscoelasticity. Biomechanics of soft and hard tissues.
BIOE 411 Tissue Engineering
Prerequisite: at least one biology course and MATH241. Recommended: BSCI330 and BIOE340. A review of the fundamental principles involved in the design of engineered tissues and organs. Both biological and engineering fundamentals will be considered.
BIOE 420 Bioimaging
Prerequisite: BIOE120, BIOE121, BIOE241, MATH246; and permission of department. Examines the physical principles behind major biomedical imaging modalities and new ways of using images for bio-related applications.
BIOE 431 Fundamentals of Biosensor Techniques, Instrumentation, and Applications
Prerequisites: CHEM135, PHYS161, PHYS261, and BSCI330. Restriction; and permission of the department. A thorough review of fundamental concepts of biosensing systems, principles of common detection methods, and modern applications of biosensors. Primarily literature driven. Students will obtain a detailed understanding of cutting-edge biosensing techniques, the instrumentation used, and the application space. Students also will develop skills in using current literature as a source of knowledge.
BIOE 453 Biomaterials
Prerequisite: BIOE120, BIOE121, BIOE241, CHEM231/CHEM232, MATH246; and permission of department. Also offered as ENMA425. Credit will be granted for only one of the following: ENBE453, BIOE453 or ENMA425. Formerly ENBE453. Examination of the structure and function of natural biomaterials, and cell-extracellular matrix interactions. Study physical properties of synthetic biomaterials for biomedical applications. Understanding molecular level interactions between biomolecules and biomaterials to design novel biomaterials with desirable characteristics. Application of biomaterials as implants, drug delivery systems, biosensors, engineered materials such as artificial skin and bone growth scaffolds will be covered.
BIOE 457 Biomedical Electronics & Instrumentation
Prerequisites: BIOE120, BIOE121, BIOE241, PHYS261; and permission of department. Students learn fundamental concepts of electronics, assembly of electronic components into functional circuits, and integration of functional electronic devices and circuits into a system. In the lab component, students will learn to assemble and evaluate circuits and systems.
BIOE 461 Synthetic Biology and Biological Engineering
Prerequisite: Permission of department. This course will introduce students to the scientific foundation and concepts of synthetic biology and biological engineering. Current examples that apply synthetic biology to fundamental and practical challenges will be emphasized. The course will also address the societal issues of synthetic biology, and briefly examine interests to regulate research in this area.
BIOE 471 Biological Systems Control
Prerequisite: Permission of department. Credit will be granted for only one of the following: BIOE471 or ENBE471. Formerly ENBE471. Principles of control systems designed by biological engineers and analysis of control mechanisms found in biological organisms. Apparent control strategies used by biological systems will be covered.
BIOE 485 Capstone Design I: Entrepreneurship, Regulatory Issues, and Ethics
Prerequisite: 21 required credit hours in bioengineering and permission of department. Senior standing. Credit will be granted for only one of the following: BIOE485 or ENBE485. Formerly ENBE485. This is the first part of a two-semester senior capstone design course which covers principles involved in engineering design, design approaches, economics of design, ethics in engineering, and patent regulations. It also helps students learn team work and write design project proposals under the mentorship of a faculty advisor.
BIOE 486 Capstone Design II
Prerequisite: BIOE485 taken in the immediately preceding semester and permission of department. Senior standing. Credit will be granted for only one of the following: BIOE486 or ENBE486. Formerly ENBE486. This is the second part of the senior capstone design course. This part is independent instruction where faculty mentoring each project team works with students to order supplies, fabricate their proposed design under BIOE485, test the design, write the report and present it to their fellow seniors and board of faculty mentors. Students are taught to convert the blue print of a design to actual device and test it.