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Cell and Microenvironmental Engineering Lab

Principal Investigator: 
1127 and 1207 Chemical and Nuclear Engineering Building

Research in the Cell and Microenvironment Engineering Lab lies at the interface of cell engineering, nano/microtechnology, and quantitative mechanobiology, and integrates principles and techniques from engineering, biology, and physics in order to address questions related to physiological processes and diseases such as cancer and cardiovascular disease. Our goal is to utilize this highly interdisciplinary approach in order to create relevant in vitro models of multi-scale biological systems (from intracellular signaling to single cell behavior to multicellular complexes), to understand how cells respond to physical and biochemical cues from their microenvironment, and to develop regenerative therapies for diseases using engineering strategies. We are particularly interested in questions at the interface of nano/microtechnology and blood-brain barrier mechanobiology, nuclear mechanics, and stem cell engineering.