BioE Home
Return to Faculty Directory »  |  Return to Laboratories »

Shapiro, Ben

Ben Shapiro
2246 Jeong H. Kim Engineering Building
Lab Description

News About This Professor

Research Interests 

Control of micro-scale systems, fluid dynamics, biochemicals.


Ph.D., California Institute of Technology, 1999


Dr. Benjamin Shapiro received his bachelors degree from the Aerospace Engineering department at the Georgia Institute of Technology, and his Ph.D. in Control and Dynamical Systems from Caltech. He has been at the University of Maryland since 2000, and joined the Fischell Department of Bioengineering in 2010. His research is focused on modeling, design, and control of micro-scale systems for chemical, biological, and clinical applications. He holds a joint appointment with the Institute for Systems Research and the Maryland NanoCenter, and is affiliated with the Applied Math and Scientific Computation program.

Dr. Shapiro is the recipient of a 2003 NSF CAREER award, and a Fulbright Scholarship. He has filed16 patents based on his research, two of which were awarded 1st and 3rd places in the university's annual Office of Technology Commercialization's Invention of the Year competition. He was born in Jerusalem, Israel in 1973.

Honors and Awards 

  • 2009 Fulbright Scholar (to Germany) for precision control of magnetic drug delivery to focus chemotherapy to deep tissue tumors. Host: Andreas Lubbe, Director Cecilienklinik (a 750 bed hospital), Bad Lippspringe, Germany.
  • 2007-2008 Outstanding Professor AIAA award. Each year students in the Aerospace department vote for the “… professor deemed to be the best teacher in courses over the past academic year”.
  • 2007, nominated by Maryland Science Academy for Outstanding Young Engineer award.
  • 2006, selected for membership in Council of Outstanding Young Engineering Alumni, Georgia Institute of Technology. Membership is reserved for alumni of the engineering college under forty years of age who have distinguished themselves through professional practice and or service to GT, the profession, or society-at-large.
  • 2005-2006 Outstanding Professor AIAA award.

* For a complete list of honors and awards, please visit Professor Shapiro's web site

Professional Memberships 

  • Applied Math and Scientific Computation Program

Books and Chapters 

Books edited

J. Gorman, B.Shapiro, co-editors of “Control of MEMS to Atoms”. Springer Verlag, ISBN (1441958312), 2012 edition (16 Dec 2011). Also on Amazon. (Read the related news story.)

Chapters in books

F.Yesilkoy, C.Ropp, Z.Cummins, R.Probst, E.Waks, B.Shapiro, M.Peckerar*, “New Applications and Emerging Technologies”, editor M.Feldman, chapter in “Nanolithograpy: The Art of Fabricating Nanoelectronic, Nanophotonic, and Nanobiologic Devices and Systems”, Woodhead Publishing LTD, Cambridge, 2012.

M.Armani*, Z.Cummins*, J.Gong, P.Mathai*, R.Probst*, C.Ropp, E.Waks, S.Walker*, B.Shapiro, “Feedback Control of Micro-Flows”, chapter for “Control of MEMS to Atoms”, editors J.Gorman and B.Shapiro, Springer Verlag, 2012.

A.Komaee*, R.Lee, A.Nacev*, R.Probst*, A.Sarwar*, I.Rutel, D.Depireux, K.Dormer, B.Shapiro, “Putting Therapeutic Nanoparticles Where They Need To Go By Magnet Systems Design and Control”, editor TK Thanh, chapter in “Magnetic Nanoparticles: From Fabrication to Biomedical and Clinical Applications”, CRC Press/Taylor & Francis, Jan, 2012.

M.Armani*, R.Probst*, B.Shapiro, “Fabricating Micro-Fluidic Channels Using a Vinyl Sign Plotter", chapter for “Lab on a Chip Technology: Fabrication and Microfluidics”, editors K.E.Herold, A.Rasooly, Caister Academic Press, Aug 2009.

B.Shapiro, “Control of Microfluidics” chapter entry for “Encyclopedia of Microfluidics and Nanofluidics”, editor D. Li. Springer Verlag, Sep 2008.

Selected Publications 

For a complete list of publications, please visit Professor Shapiro's web site.

C.Ropp, Z.Cummins, S.Nah, J.T.Fourkas, B.Shapiro, E.Waks, "Nanoscale Imaging and Spontaneous Emission Control with a Single Nano-Positioned Quantum Dot", Nature Communications, vol 4, article number 1447, doi: 10.1038/ncomms2477, 5 Feb 2013

P.Mathai, P.T.Carmichael, B.Shapiro, J.A.Liddle, "Simultaneous Positioning and Orientation of Single Nano-Objects Using Flow Control", RSC Advances, 2013, vol 3, no 8, pg 2677 - 2682, Jan 2013.

Z.Shen, A.Nacev, A.Sarwar, R.Lee, D.Depireux, B.Shapiro, "Automated Fluorescence and Reflectance Co-Registered 3-D Tissue Imaging System", IEEE Transactions on Magnetics, vol 49, no 1, pg 279-284, Jan 2013.

A.Sarwar, R.Lee, D.Depireux, B.Shapiro, "Magnetic Injection of Nanoparticles into Rat Inner Ears at a Human Head Working Distance", IEEE Transactions on Magnetics, vol 49, no 1, pg 440-452, Jan 2013.

J.B.Freund, B.Shapiro, "Transport of Particles by Magnetic Forces and Cellular Blood Flow in a Model Microvessel", Physics of Fluids, vol 24, pg 051904-1 - 12, published online 29 May 2012.

A.Nacev, R.Probst, S.Kim, A.Komaee, A.Sarwar, R.Lee, D.Depireux, M.Emmert-Buck, B. Shapiro*, "Towards Control of Magnetic Fluids in Patients: Directing Therapeutic Nanoparticles to Disease Locations", IEEE Control System Magazine (CSM), vol 32, no 3, pg 32-74, June 2012. [Invited tutorial paper. With authorship and North/South labels corrected in Fig 6a]. Movies.

R.Probst, Z.Cummins, C.Ropp, E.Waks, B.Shapiro*, "Flow Control of Small Objects On-Chip: Manipulating Live Cells, Quantum Dots, and Nano-Wires", IEEE Control System Magazine (CSM), vol 32, no 2, pg 26-53, April 2012. [Invited tutorial paper.] Movies.

A.Komaee, B.Shapiro*, "Steering a Ferromagnetic Particle by Optimal Magnetic Feedback Control", IEEE Transactions on Control Systems Technology, vol 20, issue 4, pg 1011-1024, July 2012.

A.Sarwar*, A.Nemirovski, B.Shapiro, “Optimal Halbach Permanent Magnet Designs for Maximally Pulling and Pushing Nanoparticles”, Journal of Magnetism and Magnetic Materials (JMMM), vol 324, issue 5, pg 742-754, March 2012.

A.Nacev*, S.H.Kim*, J.Rodriguez-Canales, M.Tangrea, B.Shapiro, M.R. Emmert-Buck “A Dynamic Magnetic Shift Method to Increase Nanoparticle Concentration in Cancer Metastases: A Feasibility Study using Simulations on Autopsy Specimens”, International Journal of Nanmedicine (IJN), vol 2011:6, pg 2907-2923, Nov 2011.

M.Armani*, M.Tangrea, B.Shapiro, M.Emmert-Buck, E. Smela, “Quantifying mRNA Levels Across Tissue Sections with 2D-RT-qPCR”, Analytical and Bioanalytical Chemistry, vol 400, pg 3383-93, July 2011.

R.Probst*, J.Lin*, A.Komaee*, A.Nacev*, Z.Cummins*, B.Shapiro,Planar Steering of a Single Ferrofluid Drop by Optimal Minimum Power Dynamic Feedback Control of Four Electromagnets at a Distance”, Journal of Magnetism and Magnetic Materials (JMMM), vol 323, pp 885-896, April 2011.

A.Nacev*, C.Beni, O.Bruno, B.Shapiro,The Behaviors of Ferro-Magnetic Nano-Particles In and Around Blood Vessels under Applied Magnetic Fields”, Journal of Magnetism and Magnetic Materials (JMMM), vol 323, issue 6, pg 651-668, March 2011.

R.Probst*, B.Shapiro, “Three-Dimensional Electrokinetic Tweezing: Device Design, Modeling, and Control Algorithms”, Journal of Micromechanics and Microengineering, vol 21, no 2 article-number 027004, Jan 2011

P.Mathai*, A.Berglund, A.Liddle, B.Shapiro,Simultaneous Positioning and Orientation of a Single Nano-Object by Flow Control”, New Journal of Physics, vol 13, pg 013027, Jan 2011.

A.Nacev*, C.Beni, O.Bruno, B.Shapiro, “Magnetic Nanoparticle Transport within Flowing Blood and into Surrounding Tissue”, Nanomedicine, vol 5, no 9, pg 1459-1466, Nov 2010.

C.Ropp, Z.Cummins*, R.Probst*, S.Qin, J.Fourkas, B.Shapiro, E.Waks, “Positioning and Immobilization of Individual Quantum Dots with Nanoscale Precision”, NanoLetters, 10(11), pg 4673-4679, Oct 2010.

C.Ropp, R.Probst*, Z.Cummins*, R.Kumar, A.Berglund, S.Srinivasan, E.Waks, B.Shapiro, “Manipulating Quantum Dots to Nanometer Precision by Control of Flow”. NanoLetters, 10 (7), pp 2525–2530, May 2010.

Related News 

Clark School Spinout Developing Pediatric Cancer Drug Delivery System to Prevent Hearing Loss from Chemotherapy
Otomagnetics Awarded $2.3 Million Fast Track NIH/NCI SBIR Contract October 19, 2017

BIOE Capstone 2017: Projects Focus on Pediatric Care, Physical Therapy, Pulmonary Tumors, and More
BIOE hosted it's largest-ever Capstone Design competition on May 10th, 2017. May 17, 2017

Article about Otomagnetics in Action on Hearing Loss newsletter
Magnetic injection work of Shapiro, Depireux is highlighted. November 14, 2016

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More
Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place. June 28, 2016

Shapiro to deliver semi-plenary address at American Control Conference
He will speak on 'Magnetic Control of Therapy to Hard-to-Reach Disease Targets.' December 19, 2014

BMES-UMD Ice Bucket Challenge Raises Funds for ALS, Mentorship Program
The University of Maryland Biomedical Engineering Society hosted its first Ice Bucket Challenge on Oct. 16. October 29, 2014

Waks, Shapiro receive NSF EAGER grant to test spintronic devices
Devices could one day measure action of individual neurons. September 3, 2014

Shapiro's Otomagnetics Recipient of BioMaryland Center Award
Otomagnetics receives a Biotechnology Development Award through the BioMaryland Center. March 14, 2014

Delivering Drugs to Inner Ear, Eyes, and Brain Made Easier with "Magnetic Syringe"
Clark School startup Otomagnetics wins AdvaMed's Rybski MedTech Award to support further development. October 9, 2013

Shapiro, Yu Win 2013 BioE Teaching, Graduate Research Awards
Honors presented at annual "Welcome Back" seminar. September 9, 2013

Shapiro, Martin awarded MPowering seed grant for novel study of cancer cells' 'microtentacles'
The researchers will use flow control to understand how microtentacles help cancer cells spread throughout the body. September 1, 2013

Shapiro Promoted to Full Professor
Interdisciplinary professor known for work in control systems, MEMS. July 15, 2013

Clark School Faculty Members to Receive Two Seed Grants
Professors Desai and Shapiro awarded $75,000 grants for research collaborations with UMB. July 10, 2013

2013 Dean's Student Research Awards Announced
Graduate students recognized for high quality engineering research. May 7, 2013

2012-2013 BioE Undergraduate Awards
Exceptional students recognized at annual ceremony. April 9, 2013

Two BioE/ISR Professors Receive Maryland Industrial Partnership Funding
Diagnostic anSERS and Cordex Systems primed for further development of sensors, device for detection of heart disease. February 26, 2013

UMD Researchers Achieve Breakthrough in Nanoprecision Imaging
Flow control of single quantum dot enables measurements with nanoscale accuracy at lower cost February 7, 2013

Shapiro, Depireux team for series of grants to combat hearing loss
Research will advance the delivery of drug therapies to the inner ear. January 17, 2013

Controlling the Small
Shapiro's new book lays the groundwork for cross-disciplinary linking of nanoscale technology and control theory. May 14, 2012

New Awards Support Research on Neonatal Ventilator Safety, Viral Diagnostics
Shapiro, White receive inaugural innovation grants from UM-CERSI. April 5, 2012

Shapiro on Nanotech Team for Assembly of Colloidal Crystals
$1.2M National Science Foundation-sponsored research could lead to optical computing, invisibility cloaks. September 22, 2011

Capstone 2011: Improved Diagnostics and Monitoring, Surgical Devices, and Personal Technology
Learn about new products from tomorrow's innovators. June 2, 2011

Alumnus' Company Featured in Washington Post Story
CloudSolar creates enhanced biofluids for solar panels, heat transfer applications. November 19, 2010

Payne, Shapiro Join BioE Faculty
Former affiliates focus on miniaturized systems, biofabrication, nanobiotechnology. May 21, 2010

Capstone 2010: Devices for Diagnostics, Improved Treatments, and Personal Health
See projects from tomorrow's innovators. May 18, 2010

BioE Students, Alumni Win Prizes at UM $75K Business Plan Competition
Aeramatics wins its division; CloudSolar recognized for social impact. May 10, 2010

Fisher Bioreactor Wins Professor Venture Fair
Bone tissue engineering technology takes top prize. November 17, 2009