Faculty Directory

Bentley, William E.

Bentley, William E.

Robert E. Fischell Distinguished Professor
Director, Robert E. Fischell Institute for Biomedical Devices
Fischell Department of Bioengineering
Chemical and Biomolecular Engineering
5102A A. James Clark Hall

EDUCATION

 

Ph.D., University of Colorado at Boulder, 1989

 

BACKGROUND

 

William E. Bentley is the Robert E. Fischell Distinguished Professor of Engineering and was founding Chair of the Fischell Department of Bioengineering. He is currently Inaugural Director of the Robert E. Fischell Institute for Biomedical Devices. He is also appointed to the Department of Chemical and Biomolecular Engineering at the University of Maryland, College Park and the Institute for Bioscience and Biotechnology Research. At Maryland since 1989, Dr. Bentley has focused his research on the development of molecular tools that facilitate the expression of biologically active proteins, having authored over 350 related archival publications. Recent interests are on deciphering and manipulating signal transduction pathways, including those of bacterial communication networks, for altering cell phenotype. To enable discovery, his lab develops new strategies for opening ‘communication’ between devices and biological systems by the creation and facile assembly of biologically functional interfaces. These concepts are emerging within the fields of ‘biofabrication’ that exploits biological components and processes for assembly and 'bioelectronics" that interface electronics with biology. He has served on advisory committees for the NIH, NSF, DOD, DOE, FDA, USDA, and several state agencies. He has mentored more than 40 PhDs and 15 postdocs, many now in leadership roles within industry, federal agencies, and academia.  He co-founded a protein manufacturing company, Chesapeake PERL, based on insect larvae as mini bioreactors. Dr. Bentley was recipient of the SIM’s Schering-Plough Young Investigator Award, the Charles Thom Award of the SIMB, the Marvin Johnson Award of the BIOT Division in the ACS, and the AIChE’s FPB Division Award. He is also a Fellow of the ACS, AAAS, and AIMBE and is an elected member of the American Academy of Microbiology. 

 

HONORS AND AWARDS

 

For the complete list, please visit Professor Bentley's web site

  • Distinguished University Professor (2016)
  • Robert E. Fischell Distinguished Chair of Engineering (2016)
  • Charles Thom Award, Society of Industrial Microbiology and Biotechnology (2013)
  • Elected Fellow, American Chemical Society (ACS) (2013)
  • Elected Member, Electorate Nominating Committee, American Association for the Advancement of Science (2013)
  • Meeting Keynote, Upstream Processing, BIOT Division of American Chemical Society’s 245th National Meeting, New Orleans (2013)
  • AIChE Food, Pharmaceutical and Bioengineering Division Award in Chemical Engineering (2012)
  • University System of Maryland (USM) Regents’ Faculty Award for Research/Scholarship/Creative Activity (2011)
  • Robert E. Fischell Distinguished Professor (former)
  • Herbert Rabin Distinguished Professor (former)
  • Fellow, American Academy of Microbiology (AAM) (2007)
  • Fellow, American Association for the Advancement of Science (2001)
  • Fellow, American Institute for Medical and Biological Engineering (2001)
  • Maryland's Outstanding Young Engineer, Maryland Science Center (1998)
  • Washington Academy of Sciences Allen C. Davis Medal (1998)
  • Schering-Plough Young Investigator Award (1996)
  • Dow Outstanding New Faculty Award from the American Society for Engineering Education (1995)
  • Society of Industrial Microbiology Outstanding Achievement in Engineering Sciences Award

 

PROFESSIONAL MEMBERSHIPS

 

  • American Academy of Microbiology
  • American Association for the Advancement of Science
  • American Chemical Society
  • American Institute of Chemical Engineers
  • American Institute for Medical and Biological Engineering
  • Biomedical Engineering Society

 

Biomolecular and metabolic engineering; cell-cell communication; heterologous protein expression; device/bio interfaces.


  • Metabolic and Biomolecular Engineering - Quorum Sensing and in vivo Genetic Manipulation
  • Biofabrication Engineering of Biological Signaling (bBIOS)
  • Bridging the communication gap between biology and electronics through the use of redox molecules
  • Characterization of AI-2 uptake in E. coli quorum sensing circuitry
  • Development of a generic strategy for the covalent assembly of proteins onto patterned surfaces, including sensor surfaces

For more information, please visit Professor Bentley's web site.

  • For a complete list of publications, please visit Professor Bentley's web site
  • Stephens, K., Pozo, M., Tsao, C.-Y., Hauk, P., and W.E. Bentley (2019) Bacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition, Nature Communications, 10, 4129, DOI: 10.1038/s41467-019-12027-6.
  • McKay, R., Ghodasra, M., Schardt, J., Quan, D.N., Pottash, A.E., Shang, W., Jay, S.M., Payne, G.F., Chang, M.W., March, J.C., and W.E. Bentley (2018) A Platform of Genetically Engineered Bacteria as Vehicles for Localized Delivery of Therapeutics: Toward Applications for Crohn's Disease, Bioengineering and Translational Medicine, 3(3): 209-221, DOI: 10.1002/btm2.10113.
  • Tschirhart, T., Kim, E., McKay, R., Ueda, H., Wu, H.C., Pottash, A.E., Zargar, A., Negrete, A., Shiloach, J., Payne, G.F., and W.E. Bentley (2017) Electronic Control of Gene Expression and Cell Behaviour in Escherichia coli Through Redox Signaling, Nature Communications, 8:14030, DOI:10.1038/ncomms14030.
  • Hwang, I.Y., Koh, E., Wong, A., March, J.C., Bentley, W.E., Lee, Y.S., and M.W. Chang (2017) Engineered Probiotic Escherichia coli Can Eliminate and Prevent Pseudomonas aeruginosa Gut Infection in Animal Models, Nature Communications, 8, 15028, DOI:10:1038/ncomms15028.
  • Terrell J.L., Wu H.C., Tsao C.Y., Barber N.B., Servinsky M.D., Payne G.F., and Bentley W.E. (2015) Nano-guided cell networks as conveyors of molecular communication, Nature Communications, doi: 10.1038/ncomms9500.
  • Payne, G.F., Kim, E., Cheng, Y., Wu, H-C., Ghodssi, R., Rubloff, G.W., Raghavan, S.R., Culver, J.N, and W.E. Bentley (2013) Accessing Biology’s Toolbox for the Mesoscale Biofabrication of Soft Matter, Soft Matter, doi:10.1039/c3sm50527h.
  • Kim, E., Gordonov, T., Liu, Y., Bentley, W. E., and G. F. Payne (2013) Reverse engineering to suggest biologically relevant redox activities of phenolic materials, ACS Chemical Biology 8, 716-724.
  • Liba, B. D., Kim, E., Martin, A. N., Liu, Y., Bentley, W. E., and G.F. Payne (2013) Biofabricated film with enzymatic and redox-capacitor functionalities to harvest and store electrons, Biofabrication 5, 015008.
  • Wu, H. C., Tsao, C. Y., Quan, D. N., Cheng, Y., Servinsky, M. D., Carter, K. K., Jee, K. J., Terrell, J. L., Zargar, A., Rubloff, G. W., Payne, G. F., Valdes, J. J., and  W.E. Bentley (2013) Autonomous bacterial localization and gene expression based on nearby cell receptor density, Molecular Systems Biology 9, 636.
  • Bentley, W.E., and G.F. Payne (2013) Nature’s Other Self-Assemblers, Science, 341(6142): 136-137.
  • Carter, K.K., Valdes, J.J., and W.E. Bentley (2012) Pathway Engineering via Quorum Sensing and sRNA Riboregulators – Interconnected Networks and Controllers, Metabolic Engineering, 14(3): 281-288.
  • Terrell, J.L., Gordonov, T., Cheng, Y., Wu, H.C., Sampey, D., Luo, X., Tsao, C.Y., Ghodssi, R., Rubloff, G.W., Payne, G.F., and W.E. Bentley (2012) Integrated Biofabrication for Electro-Addressed In-Film Bioprocessing, Biotechnology Journal, 7(3):428-439.
  • Cheng, Y., Tsao, C.-Y., Wu, H.-C., Luo, X.L., Terrell, J.L., Betz, J., Payne, G.F., Bentley, W.E., and G.W. Rubloff (2012) Electroaddressing Functionalized Polysaccharides as Model Biofilms for Interrogating Cell Signaling, Advanced Functional Materials, 22(3):519-528.
  • Liu, Y., Terrell, J.L., Tsao, C.-Y., Wu, H.C., Jawaji, V., Kim, E., Cheng, Y., Wang, Y.F., Ulijn, R.V., Raghavan, S.R., Rubloff, G.W., Bentley, W.E., and G.F. Payne (2012) Biofabricating Multifunctional Soft Matter with Enzymes and Stimuli-Responsive Materials, Advanced Functional Materials, 22(14):3004-3012.
  • Luo, X.L., Wu, H.C., Tsao, C.-Y., Cheng, Y., Betz, J., Payne, G.F., Rubloff, G.W., and W.E. Bentley (2012) Biofabrication of Stratified Biofilm Mimics for Observation and Control of Bacterial Signaling, Biomaterials, 33(20): 5136-5143.
  • Gamby, S., Roy, V., Guo, M., Smith, J.A.I., Wang, J.X., Stewart, J.E., Wang, X., Bentley, W.E., and H.O. Sintim (2012) Altering the Communication Networks of Multispecies Microbial Systems Using a Diverse Toolbox of AI-2 Analogues, ACS Chemical Biology, 7(6):1023-1030.
  • Kim, E., Liu, Y., Bentley, W.E., and G.F. Payne (2012) Redox Capacitor to Establish Bio-Device Redox-Connectivity, Advanced Functional Materials, 22(7):1409-1416.
  • Gray, K. M., B. D. Liba, Y. Wang, Y. Cheng, G. W. Rubloff, W. E. Bentley, A. Montembault, I. Royaud, L. David, G. F. Payne (2012) Electrodeposition of a Biopolymeric Hydrogel: Potential for One-step Protein Electroaddressing. Biomacromolecules, 13(4), 1181-1189.
  • Quan, D., W.E. Bentley (2012) Gene Network Homology in Prokaryotes Using a Similarity Search Approach: Queries of Quorum Sensing Signal Transduction. PLoS Computational Biology. E1002637.
  • Tsao, C.-Y., Quan, D.Q. and W.E. Bentley (2012) Development of the Quorum Sensing Biotechnological Toolbox. Current Opinion in Chemical Engineering, DOI: 10.1016/j.coche.2012.09.008.
  • Liu, Y., J. L. Terrell, C.-Y. Tsao, H.-C. Wu, V. Javvaji, E. Kim, Y. Cheng, Y. Wang, R. V. Ulijn, S. R. Raghavan, G. W. Rubloff, W. E. Bentley, G. F. Payne. (2012) Biofabricating Multi-functional Soft Matter with Enzymes and Stimuli-Responsive Materials. Advanced Functional Materials, doi: 10.1371/journal.pcbi.1002637.
  • Tsao, C.Y., Hooshangi, S., Wu, H.C., Valdes, J.J., and W.E. Bentley (2010) Autonomous Induction of Recombinant Proteins by Minimally Rewiring Native Quorum Sensing Regulon of E. coli, Metabolic Engineering, 12(3):291-297.
  • Carter, K.K., Valdes, J.J., and W.E. Bentley (2011) Pathway Engineering via Quorum Sensing and sRNA Riboregulators – Interconnected Networks and Controllers, Metabolic Engineering, (Epub, PMID22155614).
  • Luo, X.L., Buckhout-White, S., Bentley, W.E., and G.W. Rubloff (2011) Biofabrication of Chitosan-Silver Composite SERS Substrates Enabling Quantification of Adenine by a Spectroscopic Shift, Biofabrication, 3(3):034108.
  • Cheng, Y., Luo, X., Tsao, C.-Y., Wu, H.C., Betz, J., Payne, G.F., Bentley, W.E., and G.W. Rubloff (2011) Biocompatible multi-address 3D Cell Assembly in Microfluidic Devices Using Spatially Programmable Gel Formation, Lab on a Chip, 11(14):2316-2318.
  • Kamaraju, K., Smith, J., Wang, J., Roy, V., Sintim, H.O., Bentley, W.E., and S. Sukharev (2011) Effects on Membrane Lateral Pressure Suggest Permeation Mechanisms for Bacterial Quorum Sensing Molecules, Biochemistry, 50(32):6983-93.
  • Wang, Y., Liu, Y., Cheng, Y., Kim, E., Rubloff, G.W., Bentley, W.E., and G.F. Payne (2011) Coupling Electrodeposition with Layer-by-Layer Assembly to Address Proteins within Microfluidic Channels, Advanced Materials, 23(8):5817-5821
  • Fernandes, R., Roy, V., Wu, H.C., and W.E. Bentley (2010) Engineered biological nanofactories trigger quorum sensing response in targeted bacteria, Nature Nanotechnology, 5(3)213-217.
  • Fernandes R., Luo, X., Tsao, C.-Y., Payne, G.F., Ghodssi, R., Rubloff, G.W., and W.E. Bentley (2010) Biological Nanofactories Facilitate Spatially Selective Capture and Manipulation of Quorum-Sensing Bacteria in a BioMEMS Device, Lab on a Chip, 10(9):1128-1134.
  • Roy, V., Fernandes, R., Tsao, C.Y., and W.E. Bentley (2010) Cross Species Quorum Quenching Using A Native AI-2 Processing Enzyme, ACS Chemical Biology, 5(2):223-232.
  • Yang, X.H., Kim, E., Liu, T., Shi, X.W., Rubloff, G.W., Ghodssi, R., Bentley, W.E., and G.F. Payne (2010) In-film Bioprocessing and Immunoanalysis with Electroaddressable Stimuli-Responsive Polysaccharides, Advanced Functional Materials, 20(10):1645-1652.
  • Liu, Y., Kim, E., Ghodssi, R., Rubloff, G.W., Culver, J.N., Bentley, W.E., and G.F. Payne (2010) Biofabrication to Build the Biology-Device Interface, Biofabrication, 2(2):220.
  • Li, J., Attila, C., Wang, L., Wood, T.K., Valdes, J.J., and W.E. Bentley (2007) Quorum Sensing in E. coli is Signaled by AI-2/LsrR: Effects on sRNA and Biofilm Architecture, Journal of Bacteriology, 73:4100-4109.
  • Fernandes, R., Tsao, C.Y., Hashimoto, Y., Wang, L., Wood, T.K., Payne, G.F., and W.E. Bentley (2007) Magnetic Nanofactories: Localized Synthesis and Delivery of Quorum-Sensing Signaling Molecule Autoinducer-2 to Bacterial Cell Surfaces, Metabolic Engineering, 9:228-239.
  • Kim, E.J., Kramer, S.F., Hebert, C.G., Valdes, J.J., and W.E. Bentley (2007) Metabolic Engineering of the Baculovirus-Expression System via Inverse "Shotgun" Genomic Analysis & RNA Interference (dsRNA) Increases Product Yield and Cell Longevity, Biotechnology and Bioengineering, 98:645-654.
  • March, J.C., and W.E. Bentley (2007) RNAi-based Tuning of Cell Cycling in Drosophila S2 cells- effects on Recombinant Protein Yield, Applied Microbiology and Biotechnology, 73: 1128-1135.
  • Lewandowski, A.T., Small, D.A., Chen, T., Payne, G.F., and W.E. Bentley (2006) Tyrosine-based "activatable pro-tag": enzyme-catalyzed protein capture and release, Biotechnology and Bioengineering, 93:1207-1215.
  • Chang, W., Small, D.A., Toghrol, F., and W.E. Bentley (2006) Global Transcriptome Analysis of Staphylococcus aureus Response to Hydrogen Peroxide, Journal of Bacteriology, 188:1648-1659.
  • Gonzalez Barrios, A.F., Zuo R., Hashimoto, Y., Yang, L., Bentley W.E., and T.K. Wood (2006) Autoinducer 2 Controls Biofilm Formation in Escherichia coli Through a Novel Motility Quorum-sensing Regulator (MqsR, B3022), Journal of Bacteriology, 188:205-316.
  • Li, J., Wang, L., Hashimoto, Y., Tsao, C-Y., Wood, T.K., Valdes, J.J., Zafiriou, E., and W.E. Bentley (2006) Stochastic Model of E. coli AI-2 Quorum Signal Circuit Reveals Alternative Synthesis Pathways, Nature Molecular Systems Biology.
  • Wang, L., Hashimoto, Y., Tsao, C.-Y., Valdes, J.J., and W.E. Bentley (2005) cAMP and cAMP Receptor Protein (CRP) Influence Both  Synthesis and Uptake of Extracellular Autoinducer-2 in Escherichia coli, Journal of Bacteriology, 187:2066-76.
  • Yi, H., Wu, L.Q., Rubloff, G.W., Ghodssi, R., Payne, G.F., and Bentley, W.E., (2005) Signal-Directed Sequential Assembly of Biomolecules on Patterned Surfaces. Langmuir, 2:2104-2107.
  • Bleckwenn, N. A., Golding, H., Bentley, W. E., Shiloach, J., (2005) Production of Recombinant Proteins by Vaccinia Virus in a Microcarrier Based Mammalian Cell Perfusion Bioreactor, Biotechnology and Bioengineering, 90:663-674.
  • Chang, W., Small, D.A. Toghrol, F., and W.E. Bentley (2005) Microarray Analysis of Toxicogenomic Effects of Peracetic Acid on Pseudomonas aeruginosa, Environmental Science & Technology, 39:5893-5899.
  • Chang, W., Small, D.A., Toghrol, F., and W.E. Bentley (2005) Microarray Analysis of Pseudomonas aeruginosa Reveals Induction of Pyocin Genes in Response to Hydrogen Peroxide, BMC Genomics, 6.115-129.
  • Wang, L., Li, J., March, J.C., Valdes, J.J., and W.E. Bentley (2005), luxS-Dependent Gene Regulation in Escherichia coli K-12 Revealed by Genomic Expression Profiling, Journal of Bacteriology, 187:8350-8360.
  • Yi, H., Wu, L.Q., Bentley, W.E., Ghodssi, R., Rubloff, G.W., Culver, J.N., Payne, G.F., (2005) Biofabrication with Chitosan, Biomacromolecules, 6:2881-2894.

Chapin, Wang Named 2019-2020 Fischell Fellows

Both researchers are fifth-year Ph.D. students in the Fischell Department of Bioengineering. 

Researchers Aim to Sterilize N95 Masks for Reuse

Researchers working around the clock to ease the impact of supply shortages on hospitals, care facilities

Stephens Wins First Place Dean's Doctoral Student Research Award

Kristina Stephens is a BIOE doctoral student researcher advised by William Bentley.

2020 Dean's Doctoral Student Research Awards

The competition recognizes distinguished graduate student researchers in order to help propel their careers and demonstrate the value of high-quality engineering research.

Rapidly evolving ‘smart marble’ sensors hold promise for monitoring pharmaceutical industry bioreactors and beyond

Size of the neutrally buoyant bPods has dropped from ‘baseball’ to ‘golf ball’ to ‘cherry’ in just three years.

Adams' Synthetic Biology Tools for Military Relevant Microbes

Dr. Bryn Adams is a Research Scientist at ARL, a former BIOE postdoc, and a Fischell Institute affiliate.

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

UMD Researchers Tap CRISPR Technology to Connect Biology, Electronics

Potential application for complex electronics highlighted in Nature Communications

Spurring research group creativity in the time of COVID-19

Student-faculty teams that write review articles for journals reap multiple benefits.

Researchers Develop Rapid Deployment Mask

Fischell Institute designs DIY-style mask with better filtration than cloth masks.

Researchers Work to Develop Custom Conformal N95 Respirators

Researchers are working to address the critical supply of N95 respirators resulting from the COVID-19 crisis.

NCC-PDI, MedTech Innovator Accepting Pitches for 2020 Competition

Applications are open now for the March 23 first round pitch event.

Institute Hosts AMBIC December Conference, Unveils New Research

AMBIC Industry Board members and other researchers convened to discuss new and ongoing projects.

Accepting Fischell Institute/IBBR Travel Fellowship Applications

The semi-annual fellowship is open to graduate students and postdoctoral researchers with IBBR/REFI mentors.

UMD Researchers Develop Technique to Advance Cell-Based Systems

Autonomous coordination of cell subpopulations highlighted in Nature Communications.

NSF Awards $1M Grant to UMD Researchers

The interdisciplinary project will explore the molecular connection between the gut and the nervous system.

Ghodssi Receives Senior Faculty Outstanding Research Award

The award recognizes exceptionally influential research accomplishments by Clark School faculty.

BIOE Celebrates Second REU Class

The NSF-supported program provides undergraduate students with hands-on laboratory experience.

Making “Smart” Cells Smarter

UMD researchers developed a technique to drive teams of bacteria to work together autonomously.

DoD Awards $1M to Develop Portable Medical Sensors

Redox information may hold key to rapidly diagnosing disease

Herold Announces Retirement

Keith Herold announces his retirement after 32 years at the Clark School of Engineering.

BIOE Capstone Class Presents 20 Novel Projects

Student projects include novel pediatric medical devices, a hemofiltration system, and a tracheostomy device.

Four BIOE Students Named NSF Graduate Research Fellows

Students recognized for research in immunoengineering, regenerative medicine, and more.

State and University Officials Celebrate Launch of Biomedical Device Institute

University of Maryland establishes Robert E. Fischell Institute for Biomedical Devices to propel advancements in human health.

FDA Awards $5 Million to Pediatric Device Consortium

National Capital Consortium co-led by Children's National and University of Maryland

M-CERSI Cooperative Agreement Grant Renewed by Food and Drug Administration

Latest renewal allows for up to $5 million per year over five years.

NSF grant for Ghodssi, Bentley furthers research of flexible devices to combat biofilms

The researchers will combine applied microbiology with engineering disciplines to explore the complex interactions between flexible sensors, bacterial biofilms, and bioelectric treatment.

‘Smart Marbles’ hold promise for better outcomes from bioreactors

The marbles, or 'bPods,' will contain microsystems that can “eavesdrop on biology” during fermentation, cell or culture-growing processes.

Bridging the Gap between Microelectronics, Biological Systems

UMD researchers receive $1.5 M NSF grant to develop first-of-kind bioelectronics.

New Findings Demonstrate How the Food We Eat Affects Biochemical Signals in the Gut

Research collaboration sheds light on bacteria response to sugar metabolism

UMD Welcomes East China University of Science and Technology 

ECUST Vice President Changsheng Liu Visits College Park

UMD Hosts Materials Genome Initiative Principal Investigator Meeting

270 scientists and policymakers gather to enhance U.S. competitiveness in STEM.

New microsystems detect, treat bacterial biofilms that cause post-operative infections

'Flexible impedance sensor' can fit inside urinary catheters, monitor and treat biofilms.

Ghodssi, Bentley receive NSF EAGER grant to develop ingestible capsules for medical diagnosis

"Gut-Nav" capsules will be designed to detect problems in the gastro-intestinal tract, including pancreatic cancer and inflammatory bowel disease screening.

Researchers Engineer Bacteria to Hunt Down Pathogens in the Gut

Nature Communications highlights University of Maryland alum’s latest efforts to program E.coli to combat infections.

Government, Industry, Academia Representatives Collaborate to Advance Medical Device Innovation in Maryland

Robert E. Fischell Institute for Biomedical Devices, RTI International draw capacity crowd to March 7th event.

UMD Researchers Make Strides in Schizophrenia Diagnosis Research

Blood test could help doctors more quickly diagnose schizophrenia and other disorders.

Bentley, Payne Featured in The Conversation

Distinguished University Professor William Bentley publishes piece on using electricity to control gene expression.

BIOE, IBBR Researchers Develop Electrogenetic Device for Activating Gene Expression via Electrodes

System holds promise for study of biological systems, biosensors and bio-hybrid devices.

UMD Key Partner in New National Institute for Innovation of Manufacturing Biopharmaceuticals

$250 million dollar investment will advance leadership in pharmaceutical manufacturing

Bentley Named Distinguished University Professor

Fischell Dept. of Bioengineering founding chair recognized with university's highest academic honor conferred upon faculty.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Fischell Receives National Medal of Technology and Innovation

UMD Alum, BioE Professor of Practice to Receive White House Honor

NCC-PDI Pediatric Device Competition Now Accepting Proposals From Medical Device Innovators

$250,000 to be awarded to five innovations at third annual National Capital Consortium for Pediatric Device Innovation (NCC-PDI) Competition.

BioE Researchers Develop Nano-guided Cell Networks as Conveyors of Molecular Communication

BioE Professor and Founding Chair William Bentley’s research group publishes Nature Communications paper.

Fisher Named Chair of the Fischell Department of Bioengineering

Dr. John P. Fisher to succeed Dr. William E. Bentley as department chair, effective Jan. 4, 2016.

BioE Capstone 2015: New Projects Focus on Sensorineural Hearing Loss, Injury Rehabilitation, and More

Neonatal acoustic protection device takes first place in annual design competition.

Bentley Featured in Science Update Podcast

Podcast focuses on bioengineers’ work creating bacteria that can act as smart drug delivery machines.

Bentley Contributes to The Scientist Report on Bacterial Signaling in the GI Tract

BioE Chair discusses how a bacterial signaling molecule could promote healthy gut microbiota.

A New Era in Human Health Innovation

A. James Clark Hall made possible in part by the generosity of two benefactors.

UMD Patents Compounds that Inhibit Biofilm Formation and Persistence

Patent awarded for compounds capable of fighting antibiotic-resistant bacteria

Maryland inventors issued US Patent for compounds that fight biofilms

The compounds enhance the effectiveness of conventional antibiotics and inhibit the formation and persistence of biofilms.

Second Annual Pediatric Device Innovation Competition Awards $250,000

National Capital Consortium for Pediatric Device Innovation (NCC-PDI) recognizes five innovators.

University of Maryland Breaks Ground for A. James Clark Hall

New building to serve as hub for human health innovation in the state of Maryland

UMD Researchers Bridge Gap between Microelectronics, Biological Systems

“Electronic modulation of biochemical signal generation” published in Nature Nanotechnology

UMD, GBSI Partner to Advance Antibody Standards

Dr. Simran Kaur named GBSI Fellow.

International research partnership leads to major publication on controlling living cells with artificial cells

Research could lead to medical therapies carried out by nonliving, artificial cells.

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

University of Maryland Baltimore & College Park Campuses To Offer Joint M.D./Ph.D. in Medicine and Bioengineering

Program will promote human health through engineering principles and medical science.

Regulatory Science Competition Winners Present Concepts to FDA

UMD and UR competition winners present competition concepts to the FDA.

UMD and JHU Students Host Research Fair

University of Maryland and Johns Hopkins University bioengineering students joined forces to host the second annual research event.

Bentley Receives ACS BIOT’s Marvin J. Johnson Award

American Chemical Society recognizes professor for contributions to the field of biotechnology.

Consortium Led by UMD and Children's National Health System Awards $250K for Pediatric Medical Devices

National Capital Consortium for Pediatric Device Innovation awards funding for new medical devices for children.

Chung Honored at Commencement

Academic director receives Dr. Marilyn Berman Pollans Outstanding Service Award for Staff

Barber Awarded Olatunji Godo Biomedical Research Scholarship

Fund established by alumnus supports BioE junior.

BioE Holds 7th Fischell Festival (VIDEO)

Annual event highlights engineering's increasing role in medicine.

BioE's Chris Jewell Named Outstanding Young Engineer

Md. Science Center honors expert in controlling immune system response.

Schultheis to Lead New UMD Regulatory Science Initiative

Former FDA branch chief to guide UMD effort to help improve food, drug, and medical device safety.

BioE and Mtech Partner with Children's National Health System to Form Pediatric Device Consortium

FDA-supported collaboration will focus on medical device design, production and regulation.

Bentley Comments on 3D-Printed Bacteria

Professor contributes thoughts on biofabrication to Chemistry World story.

BioE Hosts First Luojia International Biomedical Conference

Event fosters collaborations between UMD and Wuhan University.

M-CERSI Day Highlights Regulatory Science

Second annual showcase event held by University of Maryland's Center of Excellence in Regulatory Science and Innovation.

Bacteria Prowl for Pathogen Prey

Alumnus Matthew Wook Chang's custom E. Coli target hospital-acquired infections.

Bentley Receives Charles Thom Award

Society for Industrial Microbiology and Biotechnology honors professor for contributions to the field.

Shapiro, Yu Win 2013 BioE Teaching, Graduate Research Awards

Honors presented at annual "Welcome Back" seminar.

Bentley Elected ACS Fellow

BioE chair recognized for research and service.

Science Gets Bentley and Payne's Perspective on Self-Assembly

BioE/IBBR professors invited to share views on new materials for biomedical applications.

BioE Capstone 2013: New Products Focus on Diagnostics, Physical Therapy and More

Students' inventions address needs ranging from home care to ICU.

Bentley Discusses Alternatives to Animal Testing in PRiSM

Lab-on-a-chip devices could reduce or eliminate need.

Maryland Exchange with Italian University Boosts Research on Artificial Cells

Bioengineering grad student part of international effort to use messages sent by synthetic cells to guide natural cell activity.

2012-2013 BioE Undergraduate Awards

Exceptional students recognized at annual ceremony.

Payne Honored with Guest Professorship

Wuhan University awards three-year appointment.

UMD and JHU Students Join Forces for Research Day

"Amplifying the Field" celebrates undergraduate contributions to biomedical research.

Rappaport Wins HHMI Fellowship

Award supports senior’s efforts to develop treatments for rare genetic disorders.

New Microfluidic Device Could Speed Drug Evaluation

Meyer wins Bioscience Day Poster division for work on device capable of separating, testing distinct areas of same biofilm.

Bentley Wins AIChE Division Award

Professor will deliver plenary talk at national meeting in October.

Gordonov Completes NSF Summer Research Fellowship in Singapore

Grad student one of 15 selected for East Asia and Pacific Summer Institute.

CERSI Co-Director Bentley to Present at 2nd AIMBE Workshop Sept. 18

Presentation at NIH's Lister Hill Auditorium will focus on Shuler’s Body-on-a-Chip System.

FDA Leaders, Industry Call for Major Strides in Regulatory Science at UM CERSI Day

Over 150 government, industry, academic representatives attend new center's showcase event.

enGENEious Bentley Talks Quorum Sensing at Oxford

Professor invited to student- and postdoc-organized conference.

Fisher Promoted

Faculty member elevated to rank of full professor.

Muro Promoted

Faculty member becomes Associate Professor, receives tenure.

Capstone 2012: Innovations in Emergency Medicine, Diagnostic Tools, Physical Therapy, and More

BioE seniors present an array of new devices for improving health and safety.

Award Supports Development of Safer Batteries for Biomedical Devices

Sophomore Mian Khalid wins prestigious Howard Hughes Medical Institute fellowship for work with Kofinas Group.

2011-2012 BioE Undergraduate Awards

Exceptional students recognized by the Department, Clark School, and professional societies.

Bentley, Mansy to Explore Living/Artificial Cell Communication

International collaboration funded by new Maryland partnership with Trento, Italy.

Preventing Costly, Life-Threatening Catheter Infections

Deutsch Foundation-sponsored Clark School research offers multi-pronged attack on major medical problem.

Bacteria Programmed to Re-Create UMD Logo

Feat part of larger body of Clark School research into preventing infections.

FDA Awards UM a New Center for Regulatory Science

Center will pilot ways universities can help improve how drugs and medical devices are evaluated.

Aranda-Espinoza, Hsieh Promoted

BioE faculty members promoted to Associate Professor, receive tenure.

Fight Bacteria With Bacteria

Alumnus creates bacterium that sacrifices itself to save you.

Inoue Joins BioE as Professor of the Practice

Canon U.S. Life Sciences senior fellow developing system for rapid diagnosis of disease.

Canon U.S. Life Sciences and the University of Maryland Launch New Collaboration

Joint team to develop automated machine designed to expedite the diagnosis of infectious diseases.

Systems Researchers Partner with Trento, Italy

Joint efforts to target bioengineering, renewable energy, nanomaterials, microsystems, education.

Alumnus' Work on Artificial Intestine Featured in L.A. Times

John March (Ph.D. '05) grows cells in 3-D.

2010-2011 BioE Undergraduate Awards

Exceptional students recognized by the Department, Clark School, and professional societies.

Gupta Wins Goldwater Scholarship; Paryavi Receives Honorable Mention

Students recognized for excellence in research.

Roy Wins ACS's Peterson Award

Graduate student recognized for work on quorum sensing.

"Bacterial Dirigibles" Emerge as Next-Generation Disease Fighters

Programmable bacteria cut out the middle-man, producing medicine in the body where needed.

Bentley, Payne Receive USM Regents' Awards for Nano-, Biodevice Work

Professors recognized for exemplary scholarship and research.

BioE@UMD: Strong Performance in New Rankings Study

National Research Council ranks doctoral program in top tier.

Stewart Named 1st Huskamp Award Recipient

Endowed scholarship honors late UMD CIO, BioE Director; aids Great Expectations campaign.

BioE Offers New Online Master's Program

New flexible master's program offers working professionals entrance to high-demand discipline.

University Partners with National Cancer Institute

Bentley to provide nano-bio drug delivery expertise in close collaboration.

Payne, Shapiro Join BioE Faculty

Former affiliates focus on miniaturized systems, biofabrication, nanobiotechnology.

BioE Hosts 26th Southern Biomedical Engineering Conference

Attendees share emerging research on human health.

2009-2010 BioE Undergraduate Awards

Exceptional students recognized by the Department, Clark School, and professional societies.

Muro Wins $1.72M National Institutes of Health R01 Grant

Group to develop new treatments for genetic diseases affecting lungs, brain.

Bentley Group Research Selected for Highlights in Chemical Technology

Paper covers monitoring and controlling bacterial communication.

Gupta Wins HHMI Fellowship

Undergraduate to study quorum sensing, inhibition of bacterial communication.

Bentley Group Research Featured in Nature Nanotechnology

New, all-biological nanofactory controls bacterial communication in targeted cells.

Roy Wins Zain Award

Graduate student recognized for excellence molecular biology research.

Bentley Hosts Webinar on Quorum Sensing

Program presented by Society of Biological Engineering.

Exploring Tuberculosis' Resistance to Disinfection

Bentley, EPA colleagues provide new insight on disease's behavior.

Rubloff Group Research Selected for Highlights in Chemical Technology.

Paper covers advances in lab-on-a-chip technology.

BioE Affiliate, Collaborator Named Director of ISR

Ghodssi to take office October 1.

Shirmohammadi Named Associate Dean of Ag School

New appointment effective August 1.

Berlin Takes 2nd in Dean's M.S. Thesis Competition

New award honors outstanding research, scholarship.

Kofinas Group Wins 2nd Business Plan Competition

Haemechanics offers new blood-clotting, drug-delivering material.

Luo Wins MRS Silver Award

Postdoc recognized for work in microfluidics.

2008-2009 BioE Undergraduate Awards

Exceptional students recognized by the Department, Clark School, university, and professional societies.

Roy Takes 1st Place in GRID Cell Category

Research focuses on disrupting communication between pathogenic bacteria.

Sweet Named 2009 Fischell Fellow

BioE grad student developing oral chemotherapy drug delivery system.

Undergraduates Present Paper at NE BioE Conference

Duttaroy, Paek and Shirmohammadi describe system for assessing viability of donor kidneys.

Bentley, Kofinas Teams Are $75K Competition Finalists

Proposed new ventures include drug-screening, blood clotting inventions.

Cancer Detection Research Wins Grant

Prevent Cancer Foundation to support Chen's biopsy guidance technique.

Payne, Bentley Research Wins TEDCO Funding

Award supports efforts to commercialize chitosan-based biochip.

Bentley Featured in CNN Report on Bioterrorism

Professor comments on need for accountability.

Stephan Koev wins MEMS Alliance best poster award

Poster highlights research on optical microcantilever sensors for liquid samples.

BioE Students Win at Bioscience Day Poster Session

Luo, Roy on top in bioengineering division.

Fernandes Wins ACS's Peterson Award

Graduate student recognized for work on nanofactories.

Bentley, Hung, Culver Gene Therapy Research Covered By Wired

Repurposed virus could be used to deliver siRNA to diseased cells.

Quorum Sensing Research Wins $2.5M DoD Contract

Bioeningeering/UMBI collaborate on biological threat detection.

Genomic Research Receives EPA Award

Microarray Research Laboratory wins Scientific and Technological Achievement Award.

2008 Capstone Projects Address Human Health, Environmental Concerns

Seniors present the final projects of their undergraduate career.

Ghodssi Named Herbert Rabin Distinguished Professor

Dr. Reza Ghodssi is recognized for sustained and influential scientific and scholarly work.

Alumnus March Awarded Hartwell Foundation Grant

Funding will support development of new type 1 diabetes treatment.

Undergraduate Honors and Awards Recipients, 2007-2008

Exceptional students recognized by Department, Clark School, ASABE.

BioE Holds 2nd Annual Fischell Festival

New bioengineering wing dedicated; 2008 Fischell Fellow announced.

Dandin Named 2008 Fischell Fellow

BioE grad student to develop fast, portable biosensor.

New Bioengineering Wing Unveiled

$7.6M, 7,400-square-foot addition to Kim Building serves as new department home.

Advance in Creating in Vitro Programmable Biological Microfactories

Research team includes Bentley, Ghossi, Payne, Rubloff.

Deutsch Named Professor of the Practice

RWD Technologies founder recognized for career, support of USM.

Alumni Excel in Academia, Research

Former Bentley Group members work with "designer bacteria", therapeutics, biofuels, viruses and vaccines.

$600K Gift Creates Hong Ji Fellowship

Donation to benefit international bioengineering graduate students, Great Expectations campaign.

Bentley Named Fischell Distinguished Professor

Professorship, part of Fischell endowment, recognizes scientific and scholarly work.

Bioengineering Recognized for Accessibility

President's Commission on Disability Issues grants honor.

Fisher Named Reviews Co-Editor for Expanding Journal

Professor joins editorial team of Tissue Engineering, Part B

$2M NSF Grant for "Bacterial Communication"

Cellular and biomolecular engineering research to focus on biofunctionalized devices.

Projects Come Together at Capstone II

Seniors show the results of a year's work.

Bentley Elected to Fellowship

Fischell Department chair joins leadership of American Society of Microbiology.

Janiak Named 2007 Fischell Fellow

Student recognized for research, entrepreneurial spirit.

Bioengineering/Biological Resources Engineering Undergraduates Honored

Clark School Honors and Awards Ceremony 2006-2007

"Side Effects May Not Include…"

Clark School shows in vivo "nanofactories" can make and deliver targeted drugs.

Fisher Edits Two Works on Tissue Engineering

Work includes conference compilation, biomedical engineering handbook.

$1 Million For Nano-Bio Initiative

Deutsch Foudation will fund Clark School bioengineering research on the nanoscale.

Professor William Bentley, the Herbert Rabin Distinguished Professor of Engineering, receives the 2003 Clark School Outstanding Faculty Research Award

Dr. William Bentley, Herbert Rabin Distinguished Professor of Engineering and director of Bioengineering Program received the 2003 Clark School of Engineering Outstanding Faculty Research Award.

Bentley Named to Rabin Professorship

Professorship supports new and emerging fields in engineering.

Bioengineering Graduate Program Launched

Cross-disciplinary program focuses on biology, medicine and health.