
Clyne, Alisa Morss
Associate Chair, Diversity, Equity, and Inclusion
B.S., Mechnical Engineering, Stanford University
Dr. Clyne's Vascular Kinetics Laboratory conducts research at the interface of engineering, biochemistry, and vascular biology. In their prior work, the group largely focused on how an altered glucose environment (e.g., in diabetes) impaired endothelial cell response to shear stress and cyclic strain. Dr. Clyne and her lab have demonstrated that endothelial cells in high glucose do not respond appropriately to mechanical stimuli. Today, the group focuses primarily on the opposite question: how the mechanical environment affects endothelial cell glucose metabolism. They are integrating mechanobiology and metabolism, with the hope of using metabolic engineering to decrease the burden of cardiovascular disease and cancer. With new collaboration opportunities at the University of Maryland, Dr. Clyne and her lab group plan to extend their cell and animal work into human studies.
- Laminar and disturbed flow effects on endothelial glucose metabolism
- Computational models of endothelial glucose metabolism
- Impaired endothelial mechanosensing in pulmonary arterial hypertension
- Arterial stiffness in spinal cord injury
- Perfusion effects on cancer metabolism
- Vascular glucose transport in traumatic brain injury and Alzheimer’s disease
- Pressure myography-on-a-chip
- Energy Fields to Control Mitochondrial Metabolism
One Size Does Not Fit All
To advance inclusive medical therapies and diversity in fundamental science, one Maryland engineer leads by example.Clyne Named BIOE Associate Chair, Diversity, Equity & Inclusion
Role will support efforts to enhance diversity within the department and in the STEM fields at large.BIOE Capstone Class Virtually Presents 24 Novel Projects
BIOE seniors present Capstone projects and celebrate winners virtually.Clyne, Jewell Inducted into AIMBE College of Fellows
BIOE faculty awarded one of the highest professional distinctions accorded to a medical/biological engineer.Clyne, Maisel to Join BIOE Faculty in 2019
Associate, assistant professors bring expertise in endothelial cell biology, mucosal drug delivery.- American Heart Association
- American Institute for Medical and Biological Engineering
- American Society of Mechanical Engineers