Clyne, Alisa Morss
Associate Chair, Diversity, Equity, and Inclusion
Brain and Behavior Institute
Vascular Kinetics Laboratory
B.S., Mechanical Engineering, Stanford University
Dr. Clyne's Vascular Kinetics Laboratory conducts research at the interface of engineering, biochemistry, and vascular biology. In their prior work, the group largely focused on how an altered glucose environment (e.g., in diabetes) impaired endothelial cell response to shear stress and cyclic strain. Dr. Clyne and her lab have demonstrated that endothelial cells in high glucose do not respond appropriately to mechanical stimuli. Today, the group focuses primarily on the opposite question: how the mechanical environment affects endothelial cell glucose metabolism. They are integrating mechanobiology and metabolism, with the hope of using metabolic engineering to decrease the burden of cardiovascular disease and cancer. With new collaboration opportunities at the University of Maryland, Dr. Clyne and her lab group plan to extend their cell and animal work into human studies.
- Laminar and disturbed flow effects on endothelial glucose metabolism
- Computational models of endothelial glucose metabolism
- Impaired endothelial mechanosensing in pulmonary arterial hypertension
- Arterial stiffness in spinal cord injury
- Perfusion effects on cancer metabolism
- Vascular glucose transport in traumatic brain injury and Alzheimer’s disease
- Pressure myography-on-a-chip
- Energy Fields to Control Mitochondrial Metabolism
24 Teams Present at BIOE Capstone Competition Including First BCE StudentsOn May 8, 2023, 24 teams presented novel designs at the BIOE Capstone Design Competition.
Five BIOE Students & Alumni Named NSF Graduate Research FellowsThe NSF Graduate Research Fellowship Program (GRFP) was established to ensure the vitality and diversity of the scientific and engineering workforce of the United States.
Fischell Fellow Spotlight: Alisa ClyneClyne's area of expertise is cardiovascular mechanobiology and metabolism.
Recent Bioengineering Graduate Awarded National Mitchell ScholarshipNeelesh Mupparapu (B.S. bioengineering '22) named one of 12 winners to pursue graduate study in Ireland
Weber, Stewart Named Fischell FellowsBIOE names two recipients of prestigious department award
$7.9 Million in NIH Awards Propel UMD Aging ResearchNew multidisciplinary collaborations take on challenges like Alzheimer’s disease prevention.
BIOE Announces Spring 2022 Instructional Impact AwardsThe Fischell Department of Bioengineering honored three educators, nominated by students and peers.
BIOE Capstone Competition Highlights 24 Novel ProjectsThe Bioengineering Senior Capstone Design competition returned to in-person on Monday, May 2.
Celebrating 14 Participants of 2021 BIOE REU ProgramThe BIOE REU program promotes collaboration between UMD and the FDA, making it unlike any other in the country
Maisel to Investigate Little-Known Organ in the BodyDr. Katharina Maisel was awarded a $1.8 million NIH NIGMS grant to study the interstitium and lymphatics.
Clyne, Ma, Stroka PromotedThe three BIOE faculty are promoted to Professor, Senior Lecturer, and Associate Professor, respectively.
BIOE Capstone Projects Focus on Medical Devices, AI, and MoreBIOE seniors present 23 novel Capstone projects live via Gatherly.
Maryland Graduate Engineering Ranked #10 Public in the NationFrom extreme batteries to windows made from wood, Clark School’s trendsetting work ranks it among the country’s Top 10 public engineering schools for the 3rd consecutive year.
One Size Does Not Fit AllTo advance inclusive medical therapies and diversity in fundamental science, one Maryland engineer leads by example.
Clyne Named BIOE Associate Chair, Diversity, Equity & InclusionRole will support efforts to enhance diversity within the department and in the STEM fields at large.
BIOE Capstone Class Virtually Presents 24 Novel ProjectsBIOE seniors present Capstone projects and celebrate winners virtually.
Clyne, Jewell Inducted into AIMBE College of FellowsBIOE faculty awarded one of the highest professional distinctions accorded to a medical/biological engineer.
Clyne, Maisel to Join BIOE Faculty in 2019Associate, assistant professors bring expertise in endothelial cell biology, mucosal drug delivery.
- American Heart Association
- American Institute for Medical and Biological Engineering
- American Society of Mechanical Engineers