Faculty Directory

Jay, Steven

Jay, Steven

Associate Professor
Fischell Department of Bioengineering
3116 A. James Clark Hall


  • 2009 - 2013    Postdoctoral Fellow, Brigham and Women's Hospital/Harvard Medical School (PI: Richard T. Lee)
  • 2009 - 2013    Visiting Scientist, MIT (PI: Linda Griffith)
  • 2004 - 2009    PhD, Yale University (PI: W. Mark Saltzman)
  • 2000 - 2004    BSBE, University of Georgia


  • 2018     Graduate Faculty Mentor of the Year – University of Maryland
  • 2018     CAREER Award – National Science Foundation
  • 2018     Associate Scientific Advisory Board Member – Science Translational Medicine
  • 2016     Faculty Teaching Award – Fischell Department of Bioengineering, U. of Maryland
  • 2016     Young Innovator in Cellular and Molecular Bioengineering – Biomedical Engineering Society
  • 2015     Ralph E. Powe Junior Faculty Award – Oak Ridge Associated Universities
  • 2013     Innovation and Career Development Award – Biomedical Engineering Society (BMES)
  • 2012     Innovative Technology in Cardiovascular Sciences Award – Brigham and Women’s Hospital
  • 2012     Innovation in Biotechnology Award – American Association of Pharmaceutical Scientists
  • 2012     K99/R00 Pathway to Independence Award – National Institutes of Health
  • 2011     Breast Cancer Postdoctoral Fellowship – U.S. Department of Defense
  • 2010     F32 NRSA Postdoctoral Fellowship – National Institutes of Health (declined)
  • 2009     Henry Prentiss Becton Prize (Outstanding Ph.D. Thesis in Engineering) – Yale University


  • Biomedical Engineering Society (BMES)
  • International Society for Extracellular Vesicles (ISEV)
  • American Society of Gene & Cell Therapy (ASGCT)
  • Society for Biological Engineering (SBE)
  • American Association of Pharmaceutical Scientists (AAPS)



Extracellular vesicles, cell therapy, protein therapeutics, drug delivery, biomanufacturing


Our research aims to uncover new biological insights towards the design and development of novel biotherapeutics (aka biopharmaceuticals), including proteins, extracellular vesicles (exosomes) and others. We also strive to develop new approaches to drug delivery and biomanufacturing using fundamental tools from both engineering and biology. Employing techniques in molecular biology, protein design and engineering, biomaterials and nanotechnology, we are primarily interested in developing new biotechnologies to address clinical needs in wound repair, cardiovascular disease, cancer, brain and spinal cord injuries, neurological diseases, osteoarthritis, and sepsis, among others. Overarching goals of the lab include developing therapeutics towards clinical translation and endowing trainees with the skills and knowledge necessary to become leaders in the biotechnology and pharmaceutical industries.


Google Scholar Profile

  • BIOE340 - Modeling Physiological Systems 
  • BIOE389C - Bioengineering Design Competitions 
  • BIOE462 - Therapeutic Development and Delivery 
  • BIOE612 - Physiological Evaluation of Bioengineering Designs 

Engineering QC into Biomanufacturing of EV-based Products

Steven Jay is P.I of this M-CERSI funded project. Steven R. Bauer serves as FDA subject matter expert.

Shah Organizes Clothing Drive to Make Masks in Pandemic

The rising senior also volunteers with the Frederick Community Action Agency.

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

NIH Awards $2.8M Grant to Further Dementia Research

UMB, BIOE researchers team up to study link between spinal cord injury and dementia.

Jay Promoted to Associate Professor

BIOE's Dr. Steven Jay has been promoted to associate professor.

2019 Dean's Doctoral and Master's Student Research Awards

Created by Clark School Dean Darryll Pines, the competition recognize distinguished graduate student researchers in order to help propel their careers and demonstrate the value of high-quality engineering research.

BIOE Capstone Class Presents 20 Novel Projects

Student projects include novel pediatric medical devices, a hemofiltration system, and a tracheostomy device.

Fischell Department of Bioengineering Launches REU Program

NSF-funded summer program invites undergrads to explore new approaches to engineering cells, tissues, organs.

BIOE Recognizes Undergraduate Award Recipients

Annual honors given for outstanding academics, service.

Natalie Livingston Awarded NSF Graduate Fellowship

BIOE senior recognized for efforts to advance drug delivery research.

Three BIOE Professors Awarded NIH R01s in as Many Months

Drs. Jewell, Scarcelli, and Jay were awarded a collective total of $5.4 million in NIH R01 funding this spring.

Transforming Medicine, Impacting Health

While many freshmen were acclimating to college life, a team of first-year students was adjusting to life as biotech inventors.

Jay Awarded $2 Million NIH R01 Grant for Biotherapeutic Approach to Healing Chronic Wounds

BIOE Assistant Professor Steven Jay leads efforts to develop exosome-based therapies for wound healing.

Jay Receives National Science Foundation CAREER Award

BIOE assistant professor recognized for efforts to develop new class of biotherapeutics.

Anjana Jeyaram Named PhRMA Foundation Predoctoral Fellow

BIOE Ph.D. student recognized for her research on engineering extracellular vesicles.

Gray Wins Dr. Mabel S. Spencer Award for Graduate Achievement

BIOE Ph.D. student recognized for efforts to develop therapies for diseases of the central nervous system.

John Schardt Awarded American Association of Pharmaceutical Sciences Fellowship

BIOE graduate student recognized for design of multivalent protein therapeutics to target various cancers.

BIOE Capstone 2017: Projects Focus on Pediatric Care, Physical Therapy, Pulmonary Tumors, and More

BIOE hosted it's largest-ever Capstone Design competition on May 10th, 2017.

Patel Awarded American Heart Association Predoctoral Fellowship

BIOE graduate student recognized for efforts to advance treatments for peripheral vascular diseases.

Jay, Jewell Named 2016 Young Innovators of Cellular and Molecular Bioengineering

BIOE researchers look to advance delivery of therapeutics to treat cancers.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Jay Lab Works Toward Engineering Extracellular Vesicles as Next-Generation Biotherapeutics

BioE assistant professor receives 2015 Ralph E. Powe Junior Faculty Enhancement Award.

Schardt Awarded UMD-NCI Cancer Research Training Fellowship

BioE graduate student recognized for efforts to develop novel molecular engineering approach to breast and ovarian cancer therapy. 

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

BioE Capstone 2013: New Products Focus on Diagnostics, Physical Therapy and More

Students' inventions address needs ranging from home care to ICU.