Faculty Directory

White, Ian

White, Ian

Associate Professor
Associate Chair and Director of Undergraduate Studies
Fischell Department of Bioengineering
3112 A. James Clark Hall
Website(s):

EDUCATION

Ph.D., Stanford University, 2002

Disease detection, optical biosensors, ring resonators, SERS, lab-on-a-chip.

The White Research Group develops integrated microsystems for the diagnosis and study of disease at the cellular and molecular level. Using a combination of microfabrication techniques, we are implementing micro total analysis systems (uTAS) for three major research thrusts.

  1. Infectious disease detection. Using novel techniques, we aim to implement a uTAS that concentrates pathogens from large volume samples, recovers nucleic acids, and quantifies pathogens in the sample based on DNA signature biosensing.
  2. Understanding cancer metastasis. We are developing a new on-chip assay to identify and enrich highly tumorigenic cells using techniques in microfabrication, chemistry, and cancer biology.
  3. Point-of-sample chemical/biomolecule detection. We have developed novel 3D optofluidic surface enhanced Raman spectroscopy (SERS) scaffolds in uTAS devices to enable low-cost portable detection of chemicals and biomolecules, including pesticides, explosives, and industrial toxins.

Wei W. Yu and Ian M. White, Chromatographic separation and detection of target analytes from complex samples using inkjet printed SERS substrates, Analyst, in press.

Katayoon Saadin, Jeffrey M. Burke, Neerav P. Patel, Rebecca E. Zubajlo, and Ian M. White, Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice, Biomedical Microdevices, DOI:10.1007/s10544-013-9755-y.

Wei W. Yu and Ian M. White, Inkjet-Printed Paper-Based SERS Dipsticks and Swabs for Trace Chemical Detection, Analyst, 138, 1020-1025, 2013. DOI:10.1039/C2AN36116G. (outside front cover)

Soroush H. Yazdi and Ian M. White, Multiplexed detection of aquaculture fungicides using a pump-free optofluidic SERS microsystem, Analyst, 138, 100-103, 2013. DOI:10.1039/C2AN36232E.

Soroush H. Yazdi and Ian M. White, An Optofluidic SERS Microsystem for Sensitive and Repeatable On-Site Detection of Chemical Contaminants, Analytical Chemistry, 84, 7992-7998, 2012. DOI:10.1021/ac301747b.

Katayoon Saadin and Ian M. White, Breast cancer stem cell enrichment and isolation by mammosphere culture and its potential diagnostic applications, Expert Reviews of Molecular Diagnostics, 13, 49-60, 2013. DOI:10.1586/erm.12.117.

Ian M. White, Soroush H. Yazdi, and Wei W. Yu, Optofluidic SERS: synergizing photonics and microfluidics for chemical and biological analysis, Microfluidics and Nanofluidics, 12, 205-216, 2012. DOI:10.1007/s10404-012-0962-2

Wei W. Yu and Ian M. White, A simple filter-based approach to surface enhanced Raman spectroscopy for trace chemical detection, Analyst, 137, 168-173, 2012. DOI:10.1039/C2AN15947C.

Soroush H. Yazdi and Ian M. White, A nanoporous optofluidic microsystem for highly sensitive and repeatable SERS detection, Biomicrofluidics, 6, 014105, 2012. DOI:10.1063/1.3677369. (selected for publication in the Virtual Journal of Nanoscale Science and Technology and the Virtual Journal of Biological Physics Research)

Xudong Fan and Ian M. White, Optofluidic microsystems for chemical and biological analysis, Nature Photonics, 5, 591-597, 2011. DOI:10.1038/nphoton.2011.206.

I-Jane Chen and Ian M. White, High-sensitivity electrochemical enzyme-linked assay on a microfluidic interdigitated microelectrode, Biosensors and Bioelectronics, 26, 4375-4381, 2011. DOI:10.1016/j.bios.2011.04.044.

Wei W. Yu and Ian M. White, Inkjet Printed Surface Enhanced Raman Spectroscopy Array on Cellulose Paper, Analytical Chemistry 82, 9626-9630, 2010. DOI:10.1021/ac102475k.

Jikun Liu, Ian M. White, and Don L. DeVoe, Nanoparticle-Functionalized Porous Polymer Monolith Detection Elements for Surface-Enhanced Raman Scattering, Analytical Chemistry, 83, 2119-2124, 2011. DOI:10.1021/ac102932d.

I. M. White and X. Fan, "On the performance quantification of resonant refractive index sensors," Optics Express 16, 1020-1028 (2008).

I. M. White, J. Gohring, and X. Fan, "SERS-based detection in an optofluidic ring resonator platform," Optics Express 15, 17433-17442 (2007).

I. M. White, J. Gohring, Y. Sun, G. Yang, S. Lacey, and X. Fan, "Versatile waveguide-coupled opto-fluidic devices based on liquid core optical ring resonators," Applied Physics Letters 94, 241104 (2007).

I. M. White, J. D. Suter, H. Oveys, X. Fan, T. L. Smith, J. Zhang, B. J. Koch, and M. A. Haase, "Universal coupling between metal-clad waveguides and optical ring resonators," Optics Express 15, 646-651 (2007).

I. M. White, H. Zhu, J. D. Suter, N. M. Hanumegowda, H. Oveys, M. Zourob, and X. Fan, "Refractometric Sensors for Lab-on-a-Chip Based on Optical Ring Resonators," IEEE Sensors Journal 7, 28-35 (2007).

I. M. White, H. Oveys, X. Fan, T. L. Smith, and J. Zhang, "Integrated Multiplexed Biosensors Based on Liquid Core Optical Ring Resonators and Anti-Resonant Reflecting Optical Waveguide," Applied Physics Letters 89, 191106 (2006).

I. M. White, H. Oveys, and X. Fan, "Increasing the enhancement of SERS with dielectric microsphere resonators," April 1 issue of Spectroscopy (2006).

I. M. White, H. Oveys, and X. Fan, "Liquid Core Optical Ring Resonator Sensors," Optics Letters 31, 1319-1321 (2006).

BIOE Capstone Class Presents 20 Novel Projects

Student projects include novel pediatric medical devices, a hemofiltration system, and a tracheostomy device.

BIOE Capstone 2017: Projects Focus on Pediatric Care, Physical Therapy, Pulmonary Tumors, and More

BIOE hosted it's largest-ever Capstone Design competition on May 10th, 2017.

White Named University of Maryland 2016 Faculty Advisor of the Year

BIOE associate chair and director of undergraduate studies honored during 21st Annual Undergraduate Studies Advising Conference.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Leonard to be Honored for Cooperative Control Innovations

Alumna Naomi Leonard to be inducted into Innovation Hall of Fame on Nov. 9.

Sensing Drugged Driving: Fischell Researchers Receive SBIR for Roadside Drug Test

Diagnostic anSERS Inc. awarded $150,000 NSF grant to develop paper-based test to identify drivers under the influence of illegal drugs.

BioE Capstone 2015: New Projects Focus on Sensorineural Hearing Loss, Injury Rehabilitation, and More

Neonatal acoustic protection device takes first place in annual design competition.

UMD Clark School Highlights Disaster Resilience at Mpact Week

Five-day event focused on role of engineers in disaster prevention, mitigation, and response.

2014 Fischell Festival Tackles Key Topics in Biomedical Emergency Response

Keynote Speaker Rear Admiral Stephen Redd (CDC) discusses Ebola treatment, prevention efforts.

Hydrophobically Modified Polymers Create “Cell Gels”

New technique could be used in tissue engineering, 3D cell culture.

Diagnostic anSERS introduces SERS sensor 'for the mainstream'

UMD alumni/student company's product can detect trace chemicals for only a few dollars per test.

Clark School Faculty Promotions Announced

Faculty promoted to full professor, associate professor with tenure.

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

UMD Launches Online Course for Transitioning Service Members and Veterans on Energy Problem Solving

Engineering course supported by Department of Defense will focus on design skills

Hoppmann Wins GRID Division for Presentation on Dipstick Sensors

Technology could be used for fast, efficient diagnosis of infectious disease.

UMD and JHU Students Join Forces for Research Day

"Amplifying the Field" celebrates undergraduate contributions to biomedical research.

Two BioE/ISR Professors Receive Maryland Industrial Partnership Funding

Diagnostic anSERS and Cordex Systems primed for further development of sensors, device for detection of heart disease.

Diagnostic anSERS Heads to Cupid's Cup Finals

Printed sensors team to vie for $70,000 in April.

White Group Sensors Paper a Royal Society of Chemistry Hot Pick

P-SERS technology to be featured on cover of Analyst.

New Awards Support Research on Neonatal Ventilator Safety, Viral Diagnostics

Shapiro, White receive inaugural innovation grants from UM-CERSI.

White Receives Best Paper Award from Sensors

Top journal recognizes work on new biosensor technology.

White's Research Wins Prestigious NSF CAREER Award

Inkjet-printed paper biosensors will reduce cost of diagnosing epidemic pathogens.

Ink Jet Printer Could Make Advanced Analysis Affordable, Accessible

White, Yu publish experiments with off-the-shelf products that could make spectroscopy easier for labs; new technique covered by CE&N.

BioE Hosts Teachers in NSF-Sponsored Program

Summer workshop will improve K-12 engineering, math education.

Herold Edits 2 Vol. Book on Biosensors, Biodetection

Titles part of Methods in Molecular Biology series.

BioE Welcomes 3 New Faculty Members

Balaras, Muro and White arrive for Fall '08.