Faculty Directory

White, Ian

White, Ian

Associate Professor
Associate Chair and Director of Undergraduate Studies
Fischell Department of Bioengineering
3112 A. James Clark Hall
Website(s):

EDUCATION

 

Ph.D., Stanford University, 2002

 

At the Amplified Molecular Sensors Lab, we aim to overcome the challenges that are preventing the realization of the next generation of biosensing and diagnostic systems. In particular, we emphasize the development and application of novel amplification strategies to add orders of magnitude improvement to chemical and biomolecular sensing, while at the same time improving the simplicity and usability of sensors and diagnostic systems.


At the Amplified Molecular Sensors Lab, we aim to overcome the challenges that are preventing the realization of the next generation of biosensing and diagnostic systems. In particular, we emphasize the development and application of novel amplification strategies to add orders of magnitude improvement to chemical and biomolecular sensing, while at the same time improving the simplicity and usability of sensors and diagnostic systems.

BIOE457: Biomedical Instrumentation

BIOE431: Fundamentals of Biosensing Techniques, Instrumentation, and Applications

  • Alessandra C. Zimmerman, Ian M. White, and Jason D. Kahn, "Nucleic acid-cleaving catalytic DNA for sensing and therapeutics, Talantain press, 2020.

  • Hieu T. Nguyen, Shweta Ganapati, David Watts, Imaly A. Nanayakkara, Philip DeShong, Ian M. White, A new trimodal phenotypic reporter of extended-spectrum beta-lactamase activity, ACS Infectious Disease, in press, 2019. DOI:10.1021/acsinfecdis.9b00138.

  • Imaly A. Nanayakkara and Ian M. White, Demonstration of a quantitative triplex LAMP assay with an improved probe-based readout for the detection of MRSA, Analyst, 144, 3878 - 3885, 2019. DOI:10.1039/C9AN00671K.

  • John P. Goertz, Kerry DeMella, Benjamin Thompson, Ian M. White, and Srinivasa Raghavan, Responsive capsules that enable hermetic encapsulation of contents and their thermally triggered burst-release, Materials Horizons, in press, 2019. DOI:10.1039/c9mh00309f.

  • Stephen M. Restaino and Ian M. White, A critical review of flexible and porous SERS sensors for analytical chemistry at the point-of-sample, Analytica Chimica Acta, 1060, 17-29, 2019, DOI:10.1016/j.aca.2018.11.057

  • John P. Goertz, Kenya Colvin, Andrew Lippe, John Daristotle, Peter Kofinas, and Ian M. White, Multi-Stage Chemical Heating for Instrument-Free Biosensing, ACS Applied Materials and Interfaces, 10, 33043–33048, 2018. DOI:10.1021/acsami.8b11611

  • John P. Goertz and Ian M. White, Phase-change partitions for thermal automation of multi-step reactions, Analytical Chemistry, 90, 3708–3713, 2018. DOI:10.1021/acs.analchem.7b05400.

  • Stephen M. Restaino and Ian M. White, Real-time multiplexed PCR using surface enhanced Raman spectroscopy in a thermoplastic chip, Lab on a Chip, 18, 832-839, 2018. DOI:10.1039/C7LC01227F.

  • John P. Goertz and Ian M. White, Peroxidyme-Amplified Radical Chain Reaction (PARCR): Nested Photochemical and Biochemical Positive Feedback, Angewandte Chemie, 56, 13411–13415, 2017. DOI:10.1002/anie.201706163.

  • Imaly A. Nanayakkara, Weidong Cao, and Ian M. White, Simplifying nucleic acid amplification from whole blood with direct PCR on chitosan microparticles, Analytical Chemistry, 89, 3773–3779, 2017. DOI:10.1021/acs.analchem.7b00274.

  • Adam G. Berger, Stephen M. Restaino, and Ian M. White, Vertical-flow paper SERS system for therapeutic drug monitoring of flucytosine in serum, Analytica Chimica Acta, 949C, 59-66, 2017. DOI:10.1016/j.aca.2016.10.035

  • Kunal R. Pandit, Imaly A. Nanayakkara, Weidong Cao, Srinivasa R. Raghavan, and Ian M. White, Capture and direct amplification of DNA on chitosan microparticles in a single PCR-optimal solution, Analytical Chemistry, 87, 11022-11029, 2015. DOI:10.1021/acs.analchem.5b03006

  • Kunal R. Pandit, Paul E. Rueger, Richard V. Calabrese, Srinivasa R. Raghavan, and Ian M. White, Assessment of surfactants for efficient droplet PCR in mineral oil using the pendant drop technique, Journal of Colloids and Surfaces B: Biointerfaces, 126, 489-495, 2015. DOI:10.1016/j.colsurfb.2015.01.001

  • Jeffrey M. Burke, Kunal Pandit, John P. Goertz, and Ian M. White, Fabrication of rigid microstructures with thiol-ene-based soft lithography for continuous-flow cell lysis, Biomicrofluidics, 8, 056503, 2014. DOI:10.1063/1.4897135.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Multiplex detection of DNA targets using polymerase chain reaction (PCR) and paper surface enhanced Raman spectroscopy (SERS) chromatography, Applied Spectroscopy, 68, 909-915, 2014. DOI:10.1366/14-07451.

  • Jeffrey M. Burke, Rebecca E. Zubajlo, Elisabeth Smela, and Ian M. White, High-throughput particle separation and concentration using spiral inertial filtration, Biomicrofluidics, 8, 024105 2014. DOI:10.1063/1.4870399.

  • Jordan F. Betz, Wei W. Yu, Yi Cheng, Ian M. White, and Gary W. Rubloff, Simple SERS substrates: powerful, portable, and full of potential, Physical Chemistry Chemical Physics, 16, 2224-2239, 2014. DOI:10.1039/C3CP53560F.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Inkjet-printed fluidic paper devices for chemical and biological analytics using surface enhanced Raman spectroscopy, Journal of Selected Topics in Quantum Electronics, 20, 7300510, 2014. DOI:10.1109/JSTQE.2013.2286076.

  • Soroush H. Yazdi, Kristen L. Giles, and Ian M. White, Multiplexed detection of DNA sequences using a competitive displacement assay in an microfluidic SERRS-based device, Analytical Chemistry, 85, 10605-10611, 2013. DOI:10.1021/ac402744z.

  • Eric P. Hoppmann, Wei W. Yu, and Ian M. White, Highly sensitive and flexible inkjet printed SERS sensors on paper, Methods, 63, 219-224, 2013. DOI:10.1016/j.ymeth.2013.07.010.

  • Wei W. Yu and Ian M. White, Chromatographic separation and detection of target analytes from complex samples using inkjet printed SERS substrates, Analyst, 138, 3679-3686 2013. DOI:10.1039/C3AN00673E.

  • Katayoon Saadin, Jeffrey M. Burke, Neerav P. Patel, Rebecca E. Zubajlo, and Ian M. White, Enrichment of tumor-initiating breast cancer cells within a mammosphere-culture microdevice, Biomedical Microdevices, 15, 645-655, 2013. DOI:10.1007/s10544-013-9755-y.

  • Wei W. Yu and Ian M. White, Inkjet-Printed Paper-Based SERS Dipsticks and Swabs for Trace Chemical Detection, Analyst, 138, 1020-1025, 2013. DOI:10.1039/C2AN36116G. (outside front cover)

  • Soroush H. Yazdi and Ian M. White, Multiplexed detection of aquaculture fungicides using a pump-free optofluidic SERS microsystem, Analyst, 138, 100-103, 2013. DOI:10.1039/C2AN36232E.

  • Soroush H. Yazdi and Ian M. White, Multiplexed detection of aquaculture fungicides using a pump-free optofluidic SERS microsystem, Analyst, 138, 100-103, 2013. DOI:10.1039/C2AN36232E.

  • Soroush H. Yazdi and Ian M. White, An Optofluidic SERS Microsystem for Sensitive and Repeatable On-Site Detection of Chemical Contaminants, Analytical Chemistry, 84, 7992-7998, 2012. DOI:10.1021/ac301747b.

  • Katayoon Saadin and Ian M. White, Breast cancer stem cell enrichment and isolation by mammosphere culture and its potential diagnostic applications, Expert Reviews of Molecular Diagnostics, 13, 49-60, 2013. DOI:10.1586/erm.12.117.

  • Ian M. White, Soroush H. Yazdi, and Wei W. Yu, Optofluidic SERS: synergizing photonics and microfluidics for chemical and biological analysis, Microfluidics and Nanofluidics, 12, 205-216, 2012. DOI:10.1007/s10404-012-0962-2

  • Wei W. Yu and Ian M. White, A simple filter-based approach to surface enhanced Raman spectroscopy for trace chemical detection, Analyst, 137, 168-173, 2012. DOI:10.1039/C2AN15947C.

  • Soroush H. Yazdi and Ian M. White, A nanoporous optofluidic microsystem for highly sensitive and repeatable SERS detection, Biomicrofluidics, 6, 014105, 2012. DOI:10.1063/1.3677369. (selected for publication in the Virtual Journal of Nanoscale Science and Technology and the Virtual Journal of Biological Physics Research)

  • Xudong Fan and Ian M. White, Optofluidic microsystems for chemical and biological analysis, Nature Photonics, 5, 591-597, 2011. DOI:10.1038/nphoton.2011.206.

  • I-Jane Chen and Ian M. White, High-sensitivity electrochemical enzyme-linked assay on a microfluidic interdigitated microelectrode, Biosensors and Bioelectronics, 26, 4375-4381, 2011. DOI:10.1016/j.bios.2011.04.044.

  • Wei W. Yu and Ian M. White, Inkjet Printed Surface Enhanced Raman Spectroscopy Array on Cellulose Paper, Analytical Chemistry 82, 9626-9630, 2010. DOI:10.1021/ac102475k.

  • Jikun Liu, Ian M. White, and Don L. DeVoe, Nanoparticle-Functionalized Porous Polymer Monolith Detection Elements for Surface-Enhanced Raman Scattering, Analytical Chemistry, 83, 2119-2124, 2011. DOI:10.1021/ac102932d.

Tillery Serves Community at COVID-19 Testing Sites and Local ER

Alana Tillery is one of six BIOE students recognized for outstanding acts of service amidst the pandemic.

BIOE Capstone Class Virtually Presents 24 Novel Projects

BIOE seniors present Capstone projects and celebrate winners virtually.

Better, Cheaper COVID-19 Tests

Compact, reusable system could quickly and cheaply test for multiple respiratory viruses.

BGSS Hosts Virtual "Research and Pajamas" Events

BGSS has transformed its "Research and Pizza" in person events to virtual "Research and Pajamas" gatherings.

Biocomputational Engineering Highlighted

Dr. Ian White (BIOE) is spearheading the effort to offer a biocomputational engineering major. 

Connor Hall Named Philip Merrill Presidential Scholar

Bioengineering senior recognized by UMD President Wallace D. Loh on Nov. 15th.

Duncan, Maisel Recognized by American Lung Association

Bioengineering assistant professors awarded grants to advance lung health research.

BIOE Seniors Receive ILS Honors Program Awards

Jules Allbritton-King and Connor Hall received awards from the Integrated Life Sciences Honors program.

BIOE Capstone Class Presents 20 Novel Projects

Student projects include novel pediatric medical devices, a hemofiltration system, and a tracheostomy device.

BIOE Recognizes Undergraduate Awards Recipients

Annual honors given for outstanding academics, service.

Four BIOE Students Named NSF Graduate Research Fellows

Students recognized for research in immunoengineering, regenerative medicine, and more.

BIOE Capstone 2017: Projects Focus on Pediatric Care, Physical Therapy, Pulmonary Tumors, and More

BIOE hosted it's largest-ever Capstone Design competition on May 10th, 2017.

White Named University of Maryland 2016 Faculty Advisor of the Year

BIOE associate chair and director of undergraduate studies honored during 21st Annual Undergraduate Studies Advising Conference.

Jewell Research Lab Explores New Therapies for Treatment of Juvenile Diabetes

Juvenile Diabetes Research Foundation awards Prof. Jewell $500,000 grant to study vaccine for diabetes.

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More

Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place.

Four UMD Students Named 2016 Goldwater Scholars

UMD is one of five institutions with all four nominees named scholars

Leonard to be Honored for Cooperative Control Innovations

Alumna Naomi Leonard to be inducted into Innovation Hall of Fame on Nov. 9.

Sensing Drugged Driving: Fischell Researchers Receive SBIR for Roadside Drug Test

Diagnostic anSERS Inc. awarded $150,000 NSF grant to develop paper-based test to identify drivers under the influence of illegal drugs.

BioE Capstone 2015: New Projects Focus on Sensorineural Hearing Loss, Injury Rehabilitation, and More

Neonatal acoustic protection device takes first place in annual design competition.

UMD Clark School Highlights Disaster Resilience at Mpact Week

Five-day event focused on role of engineers in disaster prevention, mitigation, and response.

BMES-UMD Ice Bucket Challenge Raises Funds for ALS, Mentorship Program

The University of Maryland Biomedical Engineering Society hosted its first Ice Bucket Challenge on Oct. 16.

2014 Fischell Festival Tackles Key Topics in Biomedical Emergency Response

Keynote Speaker Rear Admiral Stephen Redd (CDC) discusses Ebola treatment, prevention efforts.

Diagnostic anSERS Launches Affordable Trace Technology

First cost-effective SERS sensor detects molecular fingerprints

Hydrophobically Modified Polymers Create “Cell Gels”

New technique could be used in tissue engineering, 3D cell culture.

Diagnostic anSERS introduces SERS sensor 'for the mainstream'

UMD alumni/student company's product can detect trace chemicals for only a few dollars per test.

Clark School Faculty Promotions Announced

Faculty promoted to full professor, associate professor with tenure.

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More

Students' inventions range from diagnostic devices to accident prevention products.

UMD Launches Online Course for Transitioning Service Members and Veterans on Energy Problem Solving

Engineering course supported by Department of Defense will focus on design skills

ResearchFest 2013

ResearchFest 2013

Shapiro, Yu Win 2013 BioE Teaching, Graduate Research Awards

Honors presented at annual "Welcome Back" seminar.

BioE Capstone 2013: New Products Focus on Diagnostics, Physical Therapy and More

Students' inventions address needs ranging from home care to ICU.

Hoppmann Wins GRID Division for Presentation on Dipstick Sensors

Technology could be used for fast, efficient diagnosis of infectious disease.

2012-2013 BioE Undergraduate Awards

Exceptional students recognized at annual ceremony.

Diagnostic anSERS Takes 3rd and UMD Prize at Cupid's Cup Finals

Startup wins $10,000, plans to scale up manufacturing.

UMD and JHU Students Join Forces for Research Day

"Amplifying the Field" celebrates undergraduate contributions to biomedical research.

Two BioE/ISR Professors Receive Maryland Industrial Partnership Funding

Diagnostic anSERS and Cordex Systems primed for further development of sensors, device for detection of heart disease.

Diagnostic anSERS Heads to Cupid's Cup Finals

Printed sensors team to vie for $70,000 in April.

Chen Bioimaging Research Wins Prestigious NSF CAREER Award

Grant supports improvements to neural imaging and image-guided neurosurgery.

Diagnostic anSERS Pitches Dingman...and Wins!

BioE startup company wins funding for paper-based sensor product.

White Group Sensors Paper a Royal Society of Chemistry Hot Pick

P-SERS technology to be featured on cover of Analyst.

Capstone 2012: Innovations in Emergency Medicine, Diagnostic Tools, Physical Therapy, and More

BioE seniors present an array of new devices for improving health and safety.

BioE Teams at $75K Business Plan Competition Finals

New companies pitch products for food safety, diagnostics, detection of toxins.

Yu Takes Second at GRID Session for Advances in Sensor Technology

Grad student presents new alternatives to traditional SERS substrates.

New Awards Support Research on Neonatal Ventilator Safety, Viral Diagnostics

Shapiro, White receive inaugural innovation grants from UM-CERSI.

White Receives Best Paper Award from Sensors

Top journal recognizes work on new biosensor technology.

White's Research Wins Prestigious NSF CAREER Award

Inkjet-printed paper biosensors will reduce cost of diagnosing epidemic pathogens.

Inoue Joins BioE as Professor of the Practice

Canon U.S. Life Sciences senior fellow developing system for rapid diagnosis of disease.

Canon U.S. Life Sciences and the University of Maryland Launch New Collaboration

Joint team to develop automated machine designed to expedite the diagnosis of infectious diseases.

Yu's Printed Paper Sensors Talk Wins GRID Session

Grad student recognized for novel approach to spectroscopy.

Ink Jet Printer Could Make Advanced Analysis Affordable, Accessible

White, Yu publish experiments with off-the-shelf products that could make spectroscopy easier for labs; new technique covered by CE&N.

BioE Hosts Teachers in NSF-Sponsored Program

Summer workshop will improve K-12 engineering, math education.

Herold Edits 2 Vol. Book on Biosensors, Biodetection

Titles part of Methods in Molecular Biology series.

BioE Welcomes 3 New Faculty Members

Balaras, Muro and White arrive for Fall '08.