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Fisher, John

John Fisher
Fischell Family Distinguished Professor & Department Chair
Director, NIH Center for Engineering Complex Tissues
4102 A. James Clark Hall
Lab Description

News About This Professor

Research Interests 

Biomedical engineering; synthesis of novel hydrolytically degradable; implantable polymers; study and use of biomaterials for the delivery of therapeutics; scaffolds for orthopaedic tissue engineering applications; interaction of biomaterials and tissues


Ph.D., Rice University, 2003

Books and Chapters 

For a full list of books and chapters, please visit Professor Fisher's web site »

EE Coates and JP Fisher. Cartilage Tissue Engineering. In: The Biomedical Engineering Handbook, 4th Edition: Tissue Engineering and Artificial Organs. (Bronzino, ed.) CRC Press, Boca Raton, FL. In Press.

MEO Wang and JP Fisher. Signal Expression in Engineered Tissues. In: The Biomedical Engineering Handbook, 4th Edition: Tissue Engineering and Artificial Organs. (Bronzino, ed.) CRC Press, Boca Raton, FL. In Press.

AB Yeatts and JP Fisher. Biological Implications of Polymeric Scaffolds for Bone Tissue Engineering Developed Via Solid Freeform Fabrication. In: Handbook of Intellegent Scaffolds for Regenerative Medicine. (Khang, ed.) Pan Stanford Publishing, New Jersey. In Press.

K Kim, M Patel, and JP Fisher. Nanobiomaterials for Musuloskeletal Tissue Engineering. In: Bionanomaterials Handbook. (Sitharaman, ed.) CRC Press, Taylor & Francis, London. In Press.

EE Coates and JP Fisher. Cartilage Engineering: Current Status and Future Trends. In: Biomaterials for Tissue Engineering Applications: A Review of the Past and Future Trends. (Burdick and Mauck, eds.) Springer, New York, NY. 279-306 (2011).

D Dean, J Wallace, K Kim, AG Mikos, and JP Fisher. Stereolithographic Rendering of Low Molecular Weight Polymer Scaffolds for Bone Tissue Engineering. In: Innovative Developments in Design and Manufacturing–Advanced Research in Virtual and Rapid Prototyping. Taylor & Francis, London. In Press.

L Procter, EE Falco, JP Fisher, and JS Roth. Abdominal Wall Hernias and Biomaterials. In: Bioengineering Research of Chronic Wounds. (Gefen, ed.) Springer, New York, NY. 425-447 (2010).

DM Yoon and JP Fisher. Natural and Synthetic Polymer Scaffolds. In: Biomedical Materials. (Narayan, ed.) Springer, New York, NY. 415-442 (2009).

M Patel and JP Fisher. Biodegradable Materials for Tissue Engineering. In: McGraw-Hill 2008 Yearbook of Science and Technology. McGraw-Hill Press, New York. 39-41 (2008).

DM Yoon and JP Fisher. Polymeric Scaffolds for Tissue Engineering Applications. In: Tissue Engineering. (Bronzino, ed.) CRC Press, Boca Raton, FL. 8-1 - 8-18 (2007).

Selected Publications 

For a full list of publications, please visit Professor Fisher's web site »

AB Yeatts, DT Choquette, and JP Fisher. Bioreactors to Influence Stem Cell Fate: Augmentation of Mesenchymal Stem Cell Signaling Pathways via Dynamic Culture Systems. Biochimica et Biophysica Acta: General Subjects. In Press. (PubMed)

EE Coates, CN Riggin, and JP Fisher. Matrix Molecule Influence on Chondrocyte Phenotype and Proteoglycan 4 Expression by Alginate-Embedded Zonal Chondrocytes and Mesenchymal Stem Cells. Journal of Orthopaedic Research. In Press. (PubMed)

P Pisanti, AB Yeatts, S Cardea, JP Fisher, and E Reverchon. Tubular Perfusion System Culture of Human Mesenchymal Stem Cells on PLLA Scaffolds Produced Using a Supercritical Carbon Dioxide Assisted Process. Journal of Biomedical Materials Research, Part A. In Press. (PubMed)

S Janardhanan, MO Wang, and JP Fisher. Co-culture Strategies in Bone Tissue Engineering: The Impact of Culture Conditions on Pluripotent Stem Cell Populations. Tissue Engineering Part B: Reviews. 18: 312-321 (2012). (PubMed)

D Dean, J Wallace, A Siblani, MO Wang, K Kim, AG Mikos, and JP Fisher. Continuous Digital Light Processing (cDLP): Highly Accurate Additive Manufacturing of Tissue Engineered Bone Scaffolds. Virtual and Physical Prototyping. 7: 13-24 (2012).

AB Yeatts, EM Geibel, FF Fears, and JP Fisher. Human Mesenchymal Stem Cell Position within Scaffolds Influences Cell Fate During Dynamic Culture. Biotechnology and Bioengineering. 109:2381-2391 (2012). (PubMed)

DS Kaplan, VM Hitchins, TJ Vegella, RA Malinauskas, KM Ferlin, JP Fisher, and CG Frondoza. Centrifugation Assay for Measuring Adhesion of Serially-Passaged Bovine Chondrocytes to Polystyrene Surfaces. Tissue Engineering Part C: Methods. 18: 537-544 (2012). (PubMed)

EE Coates and JP Fisher. Gene Expression of Alginate Embedded Chondrocyte Subpopulations and Their Response to Exogenous IGF-1 Delivery. Journal of Tissue Engineering and Regenerative Medicine. 6: 179-192 (2012). (PubMed)

AB Yeatts, CN Gordon, and JP Fisher. Formation of an Aggregated Alginate Construct in a Tubular Perfusion System. Tissue Engineering Part C, Methods. 17: 1171-1178 (2011). (PubMed)

J Choi, K Kim, T Kim, G Liu, T Hyeon, MT McMahon, JW Bulte, JP Fisher, AA Gilad. Multimodal Imaging of Sustained Drug Release from 3-D Poly(Propylene Fumarate) Scaffolds. Journal of Controlled Release. 156: 239-245 (2011)

K Kim, D Dean, J Wallace, R Breithaupt, AG Mikos, and JP Fisher. The Influence of Stereolithographic Scaffold Architecture and Composition on Osteogenic Signal Expression with Rat Bone Marrow Stromal Cells. Biomaterials. 32: 3750-3763 (2011). (PubMed)

EE Falco, EE Coates, E Li, JS Roth, and JP Fisher. Fabrication and Characterization of Porous EH Scaffolds and EH-PEG Bilayers. Journal of Biomedical Materials Research, Part A. 97: 264-271 (2011). (PubMed)

EE Falco, MO Wang, JA Thompson, JM Chetta, DM Yoon, EZ Li, MM Kulkami, S Shah, A Pandit, JS Roth, and JP Fisher. Porous EH and EH-PEG Scaffolds as Gene Delivery Vehicles to Skeletal Muscle. Pharmaceutical Research. 28: 1306-1316 (2011). (PubMed)

K Kim, D Dean, A Lu, AG Mikos, and JP Fisher. Early Osteogenic Signal Expression of Rat Bone Marrow Stromal Cells is Influenced by Both Hydroxyapatite Nanoparticle Content and Initial Cell Seeding Density in Biodegradable Nanocomposite Scaffolds. Acta Biomaterialia. 7: 1249-1264 (2011). (PubMed)

AB Yeatts and JP Fisher. Tubular Perfusion System for the Long Term Dynamic Culture of Human Mesenchymal Stem Cells. Tissue Engineering Part C, Methods. 17: 337-348 (2011). (PubMed)

AB Yeatts and JP Fisher. Bone Tissue Engineering Bioreactors: Dynamic Culture and the Influence of Shear Stress. Bone. 48: 171–181 (2011). (PubMed)

CW Chen, MW Betz, JP Fisher, A Paek, and Y Chen. Macroporous Hydrogel Scaffolds and Their Characterization By Optical Coherence Tomography. Tissue Engineering Part C, Methods. 17:101-112 (2011). (PubMed)

MW Betz, JF Caccamese, DP Coletti, JJ Sauk, and JP Fisher. Challenges Associated with Orbital Floor Bone Regeneration. Tissue Engineering Part B, Reviews. 16: 541-550 (2010). (PubMed)

EE Coates and JP Fisher. Phenotypic Variations in Chondrocyte Subpopulations and Their Response to In Vitro Culture and External Stimuli. Annals of Biomedical Engineering. 38: 3371-3380 (2010). (PubMed)

K Kim, A Yeatts, D Dean, and JP Fisher. Stereolithographic Bone Scaffold Design Parameters: Osteogenic Differentiation and Signal Expression. Tissue Engineering Part B, Reviews. 16: 523-539 (2010). (PubMed)

MW Betz, AB Yeatts, WJ Richbourg, JF Caccamese, DP Coletti, EE Falco, and JP Fisher. Macroporous Hydrogels Upregulate Osteogenic Signal Expression and Promote Bone Regeneration. Biomacromolecules. 11: 1160-1168 (2010). (PubMed)

Selected Presentations 

CW Chen*, AB Yeatts, JP Fisher, and Y Chen. Fluorescent Laminar Optical Tomography for Tissue Engineering. 4th Annual Metropolitan Biophotonics Symposium. Baltimore, MD (2012).

CW Chen*, AB Yeatts, JP Fisher, and Y Chen.  Nondestructive Imaging of Stem Cells in 3D Scaffolds.  Smart Biomedical and Physiological Sensor Technology IX.  Baltimore, MD (2012).

CW Chen*, AB Yeatts, EE Coates, JP Fisher, and Y Chen. Experimental Demonstration of Angled Fluorescent Laminar Optical Tomography for Tissue Engineering.  OSA Optics and Photonics Conference: Biomedical Optics.  Miami, FL (2012).

CW Chen*, AB Yeatts, JP Fisher, and Y Chen.  Three-Dimensional Imaging of Stem Cell Distribution within Tissue Engineering Scaffolds using Angled Fluorescent Laminar Optical Tomography (aFLOT). IEEE Photonics Annual Meeting.  Arlington, VA (2011). Outstanding Best Paper Award, Third Place. 

M Shahrokh*, EE Coates, JP Fisher, and EM Powell. Delivering Hepatocyte Growth Factor as a Therapy to Treat Landau- Kleffner Syndrome. American Epilepsy Society Annual Meeting. Baltimore, MD (2011).

Related News 

Fischell Department of Bioengineering Launches REU Program
NSF-funded summer program invites undergrads to explore new approaches to engineering cells, tissues, organs. August 24, 2018

CECT Hosts 3D Bioprinting Workshop at the University of Maryland
The CECT's 3D Bioprinting Workshop took place at the University of Maryland and was a success. July 18, 2018

BIOE Recognizes Undergraduate Award Recipients
Annual honors given for outstanding academics, service. June 15, 2018

BIOE Capstone 2018: Projects Focus on Point of Care Diagnostics, Sickle Cell Disease, Neonatal Care, and More
Diagnostic device for chronic cough takes first place. June 15, 2018

UMD Welcomes East China University of Science and Technology 
ECUST Vice President Changsheng Liu Visits College Park April 17, 2018

Fisher Named Tissue Engineering Co-Editor-in-Chief
BIOE chair to serve as co-EIC of preeminent biomedical journal advancing the field of tissue engineering. January 4, 2018

Fisher Receives TERMIS-AM Senior Scientist Award
Tissue Engineering and Regenerative Medicine – Americas honors BIOE chair. December 1, 2017

University of Maryland Dedicates A. James Clark Hall
Clark Hall transforms region's biotech corridor. November 10, 2017

BIOE, ChBE Undergrads Develop Tools to Diagnose Alzheimer’s Disease before Patients Show Symptoms
"Synapto" awarded first place in 2017 NIH DEBUT Challenge August 28, 2017

Jewell Promoted to Associate Professor
Dr. Christopher Jewell named associate professor with tenure, effective July 1. July 11, 2017

Fisher, Bracaglia Weigh in on the Future of Regenerative Medicine
BIOE chair and postdoc featured in June 20th edition of On the Record. June 23, 2017

BIOE Capstone 2017: Projects Focus on Pediatric Care, Physical Therapy, Pulmonary Tumors, and More
BIOE hosted it's largest-ever Capstone Design competition on May 10th, 2017. May 17, 2017

BIOE Student Wins Prestigious Lemelson-MIT Student Prize
Lisa Tostanoski recognized for biomaterials-based strategies to combat multiple sclerosis April 19, 2017

Bentley Named Distinguished University Professor
Fischell Dept. of Bioengineering founding chair recognized with university's highest academic honor conferred upon faculty. September 7, 2016

Fisher Named Biomedical Engineering Society Fellow
Election to 2016 BMES Class of Fellows marks milestone for Fischell Department of Bioengineering. August 23, 2016

White Named University of Maryland 2016 Faculty Advisor of the Year
BIOE associate chair and director of undergraduate studies honored during 21st Annual Undergraduate Studies Advising Conference. August 11, 2016

BioE Capstone 2016: New Projects Focus on Improved Healthcare for Underserved Communities, Pediatric Patients, and More
Affordable RT-PCR for clinical diagnostics, fear mitigation device for pediatric MRIs tie for first place. June 28, 2016

Fisher Lab Researchers Examine Novel Method for 3-D Printing of Biodegradable Vascular Grafts
BioE researchers’ findings published in Advancing Healthcare Materials. December 15, 2015

Fisher Leads Overseas Project to Develop New Class of Biomaterials for Regenerative Medicine
Fischell Family Distinguished Professor Named Fulbright Scholar September 18, 2015

Novel Imaging Technique Paves Way for Advancements in Bone Tissue Engineering
BioE Associate Professor Yu Chen receives $1.29M NIH R01 grant to develop system to quantitatively image 3D cell behavior. September 3, 2015

BioE Capstone 2015: New Projects Focus on Sensorineural Hearing Loss, Injury Rehabilitation, and More
Neonatal acoustic protection device takes first place in annual design competition. May 28, 2015

BioE Researcher Wins Invention of the Year – Life Science Award
BioE Research Assistant Professor Javier Atencia-Fernandez recognized for food safety innovation. April 29, 2015

Chip Used to Separate Bacteria from Food Samples Wins Professor Venture Fair
BioE Assistant Professor Javier Atencia Named Professor Venture Fair Winner December 3, 2014

BMES-UMD Ice Bucket Challenge Raises Funds for ALS, Mentorship Program
The University of Maryland Biomedical Engineering Society hosted its first Ice Bucket Challenge on Oct. 16. October 29, 2014

Bracaglia, Melchiorri Awarded American Heart Association Predoctoral Fellowships
BioE Ph.D. students awarded two-year AHA fellowships. August 20, 2014

BioE Capstone 2014: New Projects Focus on Cardiological Health, Surgical Tools and More
Students' inventions range from diagnostic devices to accident prevention products. June 4, 2014

BioE Researchers Win Invention of the Year – Life Science Award
BioE Professor John Fisher and 2011 Fischell Fellow Anthony Melchiorri April 30, 2014

Fisher to Discuss Tissue Engineering and Biomaterials at Smithsonian Institution
“Going to Extremes: The Protective Powers of High-Tech Materials” January 9, 2014

3D-Printed Heart Implant Wins Professor Venture Fair
Polymer grafts can be custom-fitted, promote tissue growth. November 21, 2013

BioE Capstone 2013: New Products Focus on Diagnostics, Physical Therapy and More
Students' inventions address needs ranging from home care to ICU. July 11, 2013

Filling the Gaps: Making Better Bone Regeneration a Reality
Nguyen receives NSF graduate research fellowship for efforts to make bone grafts more successful. July 7, 2013

Fisher Co-Edits Book on Tissue Engineering
Tissue Engineering: Principles and Practices available from CRC Press. July 3, 2013

4 BioE Grad Students Win UMD Distinguished TA Awards
Ferlin, Ganesan, Lin and Manthe recognized by Center for Teaching Excellence. May 22, 2013

Wang Wins Wylie, Graduate All-STAR Fellowships
Awards support grad student's work in tissue engineering. May 16, 2013

Thompson Named 1 of 6 UMD Undergraduate Researchers of the Year
BioE senior recognized for work in tissue engineering. May 2, 2013

Rappaport Wins HHMI Fellowship
Award supports senior’s efforts to develop treatments for rare genetic disorders. January 24, 2013

Drug Delivery System Wins Professor Venture Fair
Muro, Ghaffarian honored at UMD Bioscience Research Day. December 11, 2012

Fisher Featured in Science Careers
Professor one of several profiled in story about careers in biomaterials research. November 20, 2012

Merrill Presidential Scholars Honored
Three Clark School students and their college and high school mentors recognized. November 2, 2012

Ferlin Elected Communications Officer of Tissue Engineering and Regenerative Medicine International Society
Grad student will serve in American Student and Young Investigator Section. June 28, 2012

Fisher Promoted
Faculty member elevated to rank of full professor. May 30, 2012

Yeatts Takes 2nd in Dean's Doctoral Research Award Competition
Grad student recognized for work in bone regeneration. May 22, 2012

Dean's Doctoral Student Research Awards Announced
Research on digital multimedia forensics, tissue engineering, rotorcraft brownout recognized. May 14, 2012

Award Supports Development of Safer Batteries for Biomedical Devices
Sophomore Mian Khalid wins prestigious Howard Hughes Medical Institute fellowship for work with Kofinas Group. April 27, 2012

2011-2012 BioE Undergraduate Awards
Exceptional students recognized by the Department, Clark School, and professional societies. April 20, 2012

Watch: BioE Freshman Stars in Integrated Life Sciences Video
Julie Etheridge profiled by Honors College program. April 6, 2012

Thompson to Study in Australia
HHMI award will support biomedical research at the University of Sydney. January 30, 2012

New Imaging Technique Covers Middle Ground Between Microscopy and Macroscopy
Chao-Wei Chen takes 3rd at photonics conference for presentation on non-invasive 3D imaging of stem cells. January 19, 2012

Fisher Elected Fellow of American Institute for Medical and Biological Engineering
Professor recognized for contributions to field of tissue engineering. December 5, 2011

$1.35 Million to Fisher Lab for Development of Bone Regeneration Technology
Implanted tissue will receive better blood supply and stronger support during healing process. October 18, 2011

Thompson Wins Outstanding ASPIRE Student Research Award
Student recognized for work on skeletal muscle regenration. April 21, 2011

2010-2011 BioE Undergraduate Awards
Exceptional students recognized by the Department, Clark School, and professional societies. April 19, 2011

A Better Way to Heal Broken Bones
Yeatts and Fisher's bioreactor work on cover of Tissue Engineering C. March 17, 2011

BioE, FDA Offer Summer Research Experiences for Undergrads
New partnership expands program, places students in federal labs. August 9, 2010

Fisher Bioreactor Wins Professor Venture Fair
Bone tissue engineering technology takes top prize. November 17, 2009

Clark School Meets Hollywood
Faculty, students appear on Science Channel, ABC, September 1, 2009

Fisher, Betz Featured on
Professor, grad student highlight tissue engineering. August 28, 2009

Shirmohammadi Named Associate Dean of Ag School
New appointment effective August 1. August 25, 2009

Fisher Named Director of Undergraduate Program
New role effective 8/24/09. August 25, 2009

Fischell Festival Video Now Online
See seminars, lectures, surgery, design projects, and more! May 12, 2009

Bone Regeneration Research Receives 5-Year NIH Funding
Fisher, Xu explore regeneration of dental tissues. April 2, 2009

Fisher Speaks at Maryland Stem Cell Symposium
Presents work on treatment of traumatic facial injuries. December 5, 2008

Fisher Receives Engalitcheff Research Funding
Distinction given by Arthritis Foundation to honor outstanding research. November 15, 2008

Lin Wins Golden Key Scholarship
BioE junior recognized for his work in the Fisher Group. October 22, 2008

Fisher Promoted
Becomes Associate Professor with tenure effective August 23. May 8, 2008

Fisher Named Reviews Co-Editor for Expanding Journal
Professor joins editorial team of Tissue Engineering, Part B September 5, 2007

Fisher On Page 1
Stem cell funding story makes front page of The Diamondback. June 15, 2007

Fisher Receives Stem Cell Funds
Research on regenerating human facial bones garners only College Park award. May 21, 2007

Fisher Named Outstanding Graduate Alumnus
Alma mater Rice University recognizes achievements. March 13, 2007

Fisher Named Reviews Editor for Tissue Engineering
Journal is the leading publication in its field. November 20, 2006

Fisher Edits Two Works on Tissue Engineering
Work includes conference compilation, biomedical engineering handbook. October 17, 2006